7ZT9

Structure of E8 TCR in complex in human MR1 bound to 4FBA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Major histocompatibility complex class I-related gene protein	polymer	290	33782.9	1	UniProt (Q95460) Pfam (PF00129) Pfam (PF07654)	Homo sapiens (human)	MHC class I-related gene protein,Class I histocompatibility antigen-like protein
2	B (B)	Beta-2-microglobulin	polymer	100	11879.4	1	UniProt (P61769) Pfam (PF07654)	Homo sapiens (human)
3	C (D)	TCR alpha	polymer	205	22884.4	1		Homo sapiens
4	D (E)	TCR beta	polymer	262	29243.3	1		Homo sapiens
5	E (A)	4-METHYLBENZOIC ACID	non-polymer		136.1	1	Chemie (4MA)
6	F, G, H, I, J... (A, E)	1,2-ETHANEDIOL	non-polymer		62.1	6	Chemie (EDO)
7	L, M, N, O (A, B, D, E)	water	water		18.0	156	Chemie (HOH)

Sequence modifications

A: 1 - 270 (UniProt: Q95460)

PDB	External Database	Details
Met 0	-	initiating methionine
Ser 261	Cys 283	conflict
Gly 271	-	expression tag
Ser 272	-	expression tag
Gly 273	-	expression tag
Gly 274	-	expression tag
Gly 275	-	expression tag
Leu 276	-	expression tag
Asn 277	-	expression tag
Asp 278	-	expression tag
Ile 279	-	expression tag
Phe 280	-	expression tag
Glu 281	-	expression tag
Ala 282	-	expression tag
Gln 283	-	expression tag
Lys 284	-	expression tag
Ile 285	-	expression tag
Glu 286	-	expression tag
Trp 287	-	expression tag
His 288	-	expression tag
Glu 289	-	expression tag

B: 1 - 99 (UniProt: P61769)

PDB	External Database	Details
Met 0	-	initiating methionine

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	97789.9
Non-Polymers*	Number of molecules	7
	Total formula weight	508.6
All*	Total formula weight	98298.5

*Water molecules are not included.