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7ZSO

human purine nucleoside phosphorylase in complex with JS-554

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C
(A, B, C)
Purine nucleoside phosphorylasepolymer28932154.93UniProt (P00491)
Pfam (PF01048)
Homo sapiens (human)PNP,Inosine phosphorylase,Inosine-guanosine phosphorylase
2D, O, S
(A, B, C)
[(~{E})-2-[2-[(4-oxidanylidene-3,5-dihydropyrrolo[3,2-d]pyrimidin-7-yl)sulfanyl]-5-[2,3,4,5,6-pentakis(fluoranyl)phenoxy]phenyl]ethenyl]phosphonic acidnon-polymer531.33Chemie (JTC)
3E, F, T
(A, C)
GLYCEROLnon-polymer92.13Chemie (GOL)
4AA, BA, G, H, I...
(C, A, B)
SULFATE IONnon-polymer96.118Chemie (SO4)
5CA, N
(C, A)
SODIUM IONnon-polymer23.02Chemie (NA)
6DA, EA, FA
(A, B, C)
waterwater18.0345Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight96464.6
Non-Polymers*Number of molecules26
Total formula weight3645.4
All*Total formula weight100110.0
*Water molecules are not included.

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PDB entries from 2025-07-02

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