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7ZSL

human purine nucleoside phosphorylase in complex with JS-196

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E...
(A, B, C, D, E...)
Purine nucleoside phosphorylasepolymer28932154.96UniProt (P00491)
Pfam (PF01048)
Homo sapiens (human)PNP,Inosine phosphorylase,Inosine-guanosine phosphorylase
2G, L, O, R, V...
(A, B, C, D, E...)
[2-[(4-oxidanylidene-3,5-dihydropyrrolo[3,2-d]pyrimidin-7-yl)sulfanyl]phenoxy]methylphosphonic acidnon-polymer353.36Chemie (JTO)
3H, M, Z
(A, B, F)
1,2-ETHANEDIOLnon-polymer62.13Chemie (EDO)
4AA, BA, I, K, N...
(F, A, B, C, D...)
SULFATE IONnon-polymer96.110Chemie (SO4)
5J, P, Y
(A, C, F)
DI(HYDROXYETHYL)ETHERnon-polymer106.13Chemie (PEG)
6CA, DA, EA, FA, GA...
(A, B, C, D, E...)
waterwater18.0946Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight192929.1
Non-Polymers*Number of molecules22
Total formula weight3584.9
All*Total formula weight196514.1
*Water molecules are not included.

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PDB entries from 2025-07-02

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