7ZQT

Helicobacter pylori adhesin BabA bound to neutralising human antibody.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, E (A, E)	Adhesin binding fucosylated histo-blood group antigen	polymer	466	49369.2	2	UniProt (O52269) Pfam (PF18304)	Helicobacter pylori
2	B, F (B, F)	Nanobody Nb19	polymer	120	13260.9	2		Lama glama
3	C, G (C, G)	VH domain human IgG antibody ABbA	polymer	222	23289.0	2		Homo sapiens
4	D, H (D, H)	VL domain human IgG antibody ABbA	polymer	211	23099.6	2		Homo sapiens (Human)
5	I, K (A, E)	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
6	J, L (A, E)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
7	M, N, O (A, E, H)	water	water		18.0	4	Chemie (HOH)

Sequence modifications

A, E: 25 - 460 (UniProt: O52269)

PDB	External Database	Details
Ala 3	-	expression tag
Ser 4	-	expression tag
Trp 5	-	expression tag
Ser 6	-	expression tag
His 7	-	expression tag
Pro 8	-	expression tag
Gln 9	-	expression tag
Phe 10	-	expression tag
Glu 11	-	expression tag
Lys 12	-	expression tag
Ser 13	-	expression tag
Gly 14	-	expression tag
Gly 15	-	expression tag
Gly 16	-	expression tag
Gly 17	-	expression tag
Gly 18	-	expression tag
Leu 19	-	expression tag
Val 20	-	expression tag
Pro 21	-	expression tag
Arg 22	-	expression tag
Gly 23	-	expression tag
Ser 24	-	expression tag
Gly 461	-	expression tag
Ser 462	-	expression tag
His 463	-	expression tag
His 464	-	expression tag
His 465	-	expression tag
His 466	-	expression tag
His 467	-	expression tag
His 468	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	218037.3
Non-Polymers*	Number of molecules	4
	Total formula weight	308.3
All*	Total formula weight	218345.6

*Water molecules are not included.