7ZNN

Cryo-EM structure of RCMV-E E27 bound to human DDB1 (deltaBPB) and full-length rat STAT2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	DNA damage-binding protein 1	polymer	840	93671.5	1	UniProt (Q16531) Pfam (PF10433) Pfam (PF03178)	Homo sapiens (human)	DDB p127 subunit,DNA damage-binding protein a,DDBa,Damage-specific DNA-binding protein 1,HBV X-associated protein 1,XAP-1,UV-damaged DNA-binding factor,UV-damaged DNA-binding protein 1,UV-DDB 1,XPE-binding factor,XPE-BF,Xeroderma pigmentosum group E-complementing protein,XPCe
2	B (B)	B27a	polymer	659	76341.9	1	UniProt (K7Y9Z1) Pfam (PF05999)	Murid betaherpesvirus 8	E27a
3	C (D)	Signal transducer and activator of transcription	polymer	845	97173.0	1	UniProt (Q5XI26) Pfam (PF02865) Pfam (PF01017) Pfam (PF02864) Pfam (PF21354) Pfam (PF00017) Pfam (PF12188)	Rattus norvegicus (Norway rat)
4	D (B)	ZINC ION	non-polymer		65.4	1	Chemie (ZN)

Sequence modifications

A: 1 - 699 (UniProt: Q16531)

PDB	External Database	Details
Gly -2	-	expression tag
Pro -1	-	expression tag
Gly 0	-	expression tag

A: 706 - 1140 (UniProt: Q16531)

PDB	External Database	Details
Gly 700	-	linker
Asn 701	-	linker
Gly 702	-	linker
Asn 703	-	linker
Ser 704	-	linker
Gly 705	-	linker

B: 1 - 656 (UniProt: K7Y9Z1)

PDB	External Database	Details
Gly -2	-	expression tag
Pro -1	-	expression tag
Gly 0	-	expression tag

D: 1 - 842 (UniProt: Q5XI26)

PDB	External Database	Details
Gly -2	-	expression tag
Pro -1	-	expression tag
Gly 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	267186.3
Non-Polymers*	Number of molecules	1
	Total formula weight	65.4
All*	Total formula weight	267251.7

*Water molecules are not included.