7ZMQ
Crystal structure of human RECQL5 helicase APO form in complex with engineered nanobody (Gluebody) G2*-006
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | ATP-dependent DNA helicase Q5 | polymer | 445 | 49537.2 | 2 | UniProt (O94762) Pfam (PF00270) Pfam (PF00271) Pfam (PF16124) | Homo sapiens (human) | DNA helicase,RecQ-like type 5,RecQ5,RecQ protein-like 5 |
| 2 | C, D (K, C) | Gluebody G2*-006 | polymer | 127 | 13803.1 | 2 | Lama glama | ||
| 3 | E, H (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | F, G, I, J (A, B) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 5 | K, L, M, N (A, B, K, C) | water | water | 18.0 | 52 | Chemie (HOH) |
Sequence modifications
A, B: 11 - 453 (UniProt: O94762)
| PDB | External Database | Details |
|---|---|---|
| Ser 9 | - | expression tag |
| Met 10 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 126680.6 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 515.1 | |
| All* | Total formula weight | 127195.7 |
