7ZML
Crystal structure of human RECQL5 helicase APO form in complex with engineered nanobody (Gluebody) G1-001
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | ATP-dependent DNA helicase Q5 | polymer | 445 | 49537.2 | 4 | UniProt (O94762) Pfam (PF00270) Pfam (PF00271) Pfam (PF16124) | Homo sapiens (human) | DNA helicase,RecQ-like type 5,RecQ5,RecQ protein-like 5 |
| 2 | E, F, G, H (K, E, F, G) | Gluebody G1-001 | polymer | 132 | 14347.8 | 4 | Lama glama | ||
| 3 | I, K, M, O (A, B, C, D) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 4 | J, L, N, P (A, B, C, D) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 5 | Q, R, S, T, U... (A, B, C, D, K...) | water | water | 18.0 | 19 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 11 - 453 (UniProt: O94762)
| PDB | External Database | Details |
|---|---|---|
| Ser 9 | - | expression tag |
| Met 10 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 255539.8 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 645.9 | |
| All* | Total formula weight | 256185.7 |
