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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

7ZME

CryoEM structure of mitochondrial complex I from Chaetomium thermophilum (state 2) - membrane arm

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
11NADH-ubiquinone oxidoreductase chain 1polymer37841716.41UniProt (G1DJA6)
Pfam (PF00146)
In PDB		Chaetomium thermophilum var. thermophilum DSM 1495Subunit ND1 of NADH-ubiquinone oxidoreductase (Complex I)
22NADH dehydrogenase subunit 2polymer57164129.21UniProt (G1DJ98)
Pfam (PF00361)
In PDB		Chaetomium thermophilum var. thermophilum DSM 1495Subunit ND2 of NADH-ubiquinone oxidoreductase (Complex I)
33NADH-ubiquinone oxidoreductase chain 3polymer14616330.01UniProt (G1DJ99)
Pfam (PF00507)
In PDB		Chaetomium thermophilum var. thermophilum DSM 1495Subunit ND3 of NADH-ubiquinone oxidoreductase (Complex I)
44NADH-ubiquinone oxidoreductase chain 4polymer54260810.31UniProt (G1DJA7)
Pfam (PF00361)
In PDB		Chaetomium thermophilum var. thermophilum DSM 1495Subunit ND4 of NADH-ubiquinone oxidoreductase (Complex I)
55NADH-ubiquinone oxidoreductase chain 5polymer67975872.01UniProt (G1DJA3)
Pfam (PF00662)
Pfam (PF00361)
Pfam (PF06455)
In PDB		Chaetomium thermophilum var. thermophilum DSM 1495Subunit ND5 of NADH-ubiquinone oxidoreductase (Complex I)
66NADH-ubiquinone oxidoreductase chain 6polymer22424819.31UniProt (G1DJ96)
Pfam (PF00499)
In PDB		Chaetomium thermophilum var. thermophilum DSM 1495Subunit ND6 of NADH-ubiquinone oxidoreductase (Complex I)
78NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7polymer8610312.81UniProt (G0SAE9)
Pfam (PF05676)
In PDB		Chaetomium thermophilum var. thermophilum DSM 1495Subunit NDUFB7 of NADH-ubiquinone oxidoreductase (Complex I)
89Subunit NDUFS5 of NADH-ubiquinone oxidoreductase (Complex I)polymer78587142.31UniProt (G0SG48)
In PDB		Chaetomium thermophilum var. thermophilum DSM 1495Subunit NDUFS5 of NADH-ubiquinone oxidoreductase (Complex I)
9DSubunit NDUFA1 of NADH-ubiquinone oxidoreductase (Complex I)polymer869833.41Chaetomium thermophilum var. thermophilum DSM 1495Subunit NDUFA1 of NADH-ubiquinone oxidoreductase (Complex I)
10JNADH-ubiquinone oxidoreductase-like proteinpolymer19921612.61UniProt (G0S2B3)
In PDB		Chaetomium thermophilum var. thermophilum DSM 1495Subunit NDUFA11 of NADH-ubiquinone oxidoreductase (Complex I)
11LNADH-ubiquinone oxidoreductase chain 4Lpolymer899838.01UniProt (G1DJA2)
Pfam (PF00420)
In PDB		Chaetomium thermophilum var. thermophilum DSM 1495Subunit ND4L of NADH-ubiquinone oxidoreductase (Complex I)
12QAcyl carrier proteinpolymer14115593.61UniProt (G0SBG9)
Pfam (PF00550)
In PDB		Chaetomium thermophilum var. thermophilum DSM 1495Subunit NDUFAB1 of NADH-ubiquinone oxidoreductase (Complex I)
13RComplex I-B22polymer9911636.51UniProt (G0SAY0)
Pfam (PF05347)
In PDB		Chaetomium thermophilum var. thermophilum DSM 1495Subunit NDUFB9 of NADH-ubiquinone oxidoreductase (Complex I)
14SComplex I-ESSSpolymer14315847.81UniProt (G0SAN0)
Pfam (PF10183)
In PDB		Chaetomium thermophilum var. thermophilum DSM 1495Subunit NDUFB11 of NADH-ubiquinone oxidoreductase (Complex I)
15UNADH-ubiquinone oxidoreductasepolymer18621517.61UniProt (G0S0R3)
Pfam (PF06747)
In PDB		Chaetomium thermophilum var. thermophilum DSM 1495Subunit NDUFA8 of NADH-ubiquinone oxidoreductase (Complex I)
16WNADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13polymer12114039.21UniProt (G0SB83)
Pfam (PF06212)
In PDB		Chaetomium thermophilum var. thermophilum DSM 1495Subunit NDUFA13 of NADH-ubiquinone oxidoreductase (Complex I)
17XNADH-ubiquinone oxidoreductase-like proteinpolymer19121645.51UniProt (G0S0S8)
Pfam (PF10785)
Pfam (PF12853)
In PDB		Chaetomium thermophilum var. thermophilum DSM 1495Subunit NUXM of NADH-ubiquinone oxidoreductase (Complex I)
18aNADH dehydrogenase (Ubiquinone)-like proteinpolymer81589210.11UniProt (G0RXU4)
Pfam (PF05821)
In PDB		Chaetomium thermophilum var. thermophilum DSM 1495Subunit NDUFB8 of NADH-ubiquinone oxidoreductase (Complex I)
19bSubunit NDUFC2 of NADH-ubiquinone oxidoreductase (Complex I)polymer9410823.51UniProt (G0S812)
In PDB		Chaetomium thermophilum var. thermophilum DSM 1495Subunit NDUFC2 of NADH-ubiquinone oxidoreductase (Complex I)
20cSubunit NDUFB3 of NADH-ubiquinone oxidoreductase (Complex I)polymer9311153.51UniProt (G0S681)
Pfam (PF08122)
In PDB		Chaetomium thermophilum var. thermophilum DSM 1495Subunit NDUFB3 of NADH-ubiquinone oxidoreductase (Complex I)
21dSubunit NDUFB10 of NADH-ubiquinone oxidoreductase (Complex I)polymer10512514.31UniProt (G0SEZ1)
In PDB		Chaetomium thermophilum var. thermophilum DSM 1495Subunit NDUFB10 of NADH-ubiquinone oxidoreductase (Complex I)
22eSubunit NDUFB2 of NADH-ubiquinone oxidoreductase (Complex I)polymer465278.11Chaetomium thermophilum var. thermophilum DSM 1495Subunit NDUFB2 of NADH-ubiquinone oxidoreductase (Complex I)
23gSubunit NDUFA3 of NADH-ubiquinone oxidoreductase (Complex I)polymer829076.51UniProt (G0RZZ2)
In PDB		Chaetomium thermophilum var. thermophilum DSM 1495Subunit NDUFA3 of NADH-ubiquinone oxidoreductase (Complex I)
24iSubunit NDUFB6 of NADH-ubiquinone oxidoreductase (Complex I)polymer9310857.31UniProt (G0S569)
In PDB		Chaetomium thermophilum var. thermophilum DSM 1495Subunit NDUFB6 of NADH-ubiquinone oxidoreductase (Complex I)
25jSubunit NDUFB4 of NADH-ubiquinone oxidoreductase (Complex I)polymer758760.31UniProt (G0S5C8)
In PDB		Chaetomium thermophilum var. thermophilum DSM 1495Subunit NDUFB4 of NADH-ubiquinone oxidoreductase (Complex I)
26nSubunit NDUFB5 of NADH-ubiquinone oxidoreductase (Complex I)polymer18420824.31UniProt (G0S086)
In PDB		Chaetomium thermophilum var. thermophilum DSM 1495Subunit NDUFB5 of NADH-ubiquinone oxidoreductase (Complex I)
271, g, n, 4, 5...1,2-Distearoyl-sn-glycerophosphoethanolaminenon-polymer748.116Chemie (3PE)
281, n, 2, 3, 4...1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINEnon-polymer790.17Chemie (PC1)
29g, 2, 4, D, XCARDIOLIPINnon-polymer1464.05Chemie (CDL)
302, 4, JLauryl Maltose Neopentyl Glycolnon-polymer1005.23Chemie (LMN)
31QS-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioatenon-polymer568.71Chemie (ZMP)
32waterwater18.0633Chemie (HOH)
Sequence modifications
5: 1 - 679 (UniProt: G1DJA3)
PDBExternal DatabaseDetails
Arg 445-insertion
Leu 446-insertion
Ala 447-insertion
Ile 448-insertion
Asp 449-insertion
Asn 450-insertion
Phe 451-insertion
Phe 452-insertion
Ser 453-insertion
Ala 454-insertion
Gln 455-insertion
Ala 456-insertion
Ile 457-insertion
Lys 458-insertion
9: 1 - 785 (UniProt: G0SG48)
PDBExternal DatabaseDetails
Val 100-insertion
a: 1 - 815 (UniProt: G0RXU4)
PDBExternal DatabaseDetails
Val 166Ala 166conflict
Ala 168Met 168conflict
-Glu 169deletion
-Gly 170deletion
-Asp 171deletion
-Pro 172deletion
-Asp 173deletion
-Pro 174deletion
n: 53 - 184 (UniProt: G0S086)
PDBExternal DatabaseDetails
Met 1-initiating methionine
Leu 2-insertion
Ala 3-insertion
Leu 4-insertion
Arg 5-insertion
Gln 6-insertion
Arg 7-insertion
Ala 8-insertion
Ala 9-insertion
Leu 10-insertion
Leu 11-insertion
Ala 12-insertion
Arg 13-insertion
Arg 14-insertion
Val 15-insertion
Arg 16-insertion
Pro 17-insertion
Thr 18-insertion
Val 19-insertion
Val 20-insertion
Val 21-insertion
Pro 22-insertion
Arg 23-insertion
Asn 24-amidation
Ala 25-insertion
Arg 26-insertion
Thr 27-insertion
Tyr 28-insertion
Ala 29-insertion
Ser 30-insertion
Ser 31-insertion
His 32-insertion
Asp 33-insertion
His 34-insertion
Asp 35-insertion
His 36-insertion
His 37-insertion
Asp 38-insertion
His 39-insertion
His 40-insertion
His 41-insertion
Asp 42-insertion
His 43-insertion
Gly 44-insertion
His 45-insertion
Asn 46-insertion
Val 47-insertion
Glu 48-insertion
Glu 49-insertion
Pro 50-insertion
Leu 51-insertion
Gly 52-insertion
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains26
Total formula weight701194.6
Non-Polymers*Number of molecules32
Total formula weight28404.5
All*Total formula weight729599.1
*Water molecules are not included.

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PDB entries from 2024-07-17

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