7ZM4
Crystal structure of HsaD from Mycobacterium tuberculosis in complex with Cyclipostin-like inhibitor CyC31
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase | polymer | 299 | 32986.6 | 2 | UniProt (P9WNH5) Pfam (PF00561) | Mycobacterium tuberculosis H37Rv | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase,HOPDA hydrolase,Meta-cleavage product hydrolase,MCP hydrolase |
| 2 | C, D (A, B) | undecyl dihydrogen phosphate | non-polymer | 252.3 | 2 | Chemie (IYB) | |||
| 3 | E (B) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | F, G (A, B) | water | water | 18.0 | 377 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 291 (UniProt: P9WNH5)
| PDB | External Database | Details |
|---|---|---|
| Lys 292 | - | expression tag |
| Leu 293 | - | expression tag |
| His 294 | - | expression tag |
| His 295 | - | expression tag |
| His 296 | - | expression tag |
| His 297 | - | expression tag |
| His 298 | - | expression tag |
| His 299 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 65973.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 600.6 | |
| All* | Total formula weight | 66573.8 |
