7ZLL

Catalytic domain of UDP-Glucose Glycoprotein Glucosyltransferase from Chaetomium thermophilum in complex with the 5-[(morpholin-4-yl)methyl]quinolin-8-ol inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	UDP-glucose-glycoprotein glucosyltransferase-like protein	polymer	299	35487.4	1	UniProt (G0SB58) Pfam (PF18404)	Chaetomium thermophilum
2	B (A)	5-(morpholin-4-ylmethyl)quinolin-8-ol	non-polymer		244.3	1	Chemie (JM3)
3	C, D, G (A)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	3	Chemie (NAG)
4	E, F (A)	alpha-D-mannopyranose	non-polymer		180.2	2	Chemie (MAN)
5	H (A)	water	water		18.0	226	Chemie (HOH)

Sequence modifications

A: 1187 - 1473 (UniProt: G0SB58)

PDB	External Database	Details
Glu 1184	-	expression tag
Thr 1185	-	expression tag
Gly 1186	-	expression tag
Gly 1474	-	expression tag
Thr 1475	-	expression tag
Lys 1476	-	expression tag
His 1477	-	expression tag
His 1478	-	expression tag
His 1479	-	expression tag
His 1480	-	expression tag
His 1481	-	expression tag
His 1482	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	35487.4
Non-Polymers*	Number of molecules	6
	Total formula weight	1268.2
All*	Total formula weight	36755.6

*Water molecules are not included.