7ZL9
Crystal structure of human GPCR Niacin receptor (HCA2)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Hydroxycarboxylic acid receptor 2,Soluble cytochrome b562 | polymer | 431 | 49817.5 | 1 | UniProt (Q8TDS4) UniProt (P0ABE7) Pfam (PF00001) | Homo sapiens (human) | G-protein coupled receptor 109A,G-protein coupled receptor HM74A,Niacin receptor 1,Nicotinic acid receptor,Cytochrome b-562 |
| 2 | B, C, D, E, F (A) | OLEIC ACID | non-polymer | 282.5 | 5 | Chemie (OLA) | |||
| 3 | G (A) | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate | non-polymer | 356.5 | 1 | Chemie (OLC) | |||
| 4 | H (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 5 | I, J, K, L, M (A) | UNKNOWN ATOM OR ION | non-polymer | 5 | Chemie (UNX) | ||||
| 6 | N (A) | water | water | 18.0 | 3 | Chemie (HOH) |
Sequence modifications
A: 1 - 1000 (UniProt: Q8TDS4)
A: 1001 - 1106 (UniProt: P0ABE7)
| PDB | External Database | Details |
|---|---|---|
| Val 70 | Ala 70 | conflict |
| Val 287 | Ser 287 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Trp 1007 | Met 29 | conflict |
| Ile 1102 | His 124 | conflict |
| Leu 1106 | Arg 128 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 49817.5 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1875.0 | |
| All* | Total formula weight | 51692.5 |
