7ZK9
ABCB1 L971C mutant (mABCB1) in the inward facing state
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | ATP-dependent translocase ABCB1 | polymer | 1260 | 139015.5 | 1 | UniProt (P21447) Pfam (PF00664) Pfam (PF00005) In PDB | Mus musculus (house mouse) | ATP-binding cassette sub-family B member 1A,MDR1A,Multidrug resistance protein 1A,Multidrug resistance protein 3,P-glycoprotein 3,Phospholipid transporter ABCB1 |
2 | A | (4~{S},11~{S},18~{S})-4,11-dimethyl-18-(sulfanylmethyl)-6,13,20-trithia-3,10,17,22,23,24-hexazatetracyclo[17.2.1.1^{5,8}.1^{12,15}]tetracosa-1(21),5(24),7,12(23),14,19(22)-hexaene-2,9,16-trione | non-polymer | 494.6 | 1 | Chemie (JIZ) |
Sequence modifications
A: 1 - 1260 (UniProt: P21447)
PDB | External Database | Details |
---|---|---|
Gln 83 | Asn 83 | engineered mutation |
Gln 87 | Asn 87 | engineered mutation |
Gln 90 | Asn 90 | engineered mutation |
Ala 133 | Cys 133 | engineered mutation |
Gly 427 | Cys 427 | engineered mutation |
Ala 713 | Cys 713 | engineered mutation |
Ala 952 | Cys 952 | engineered mutation |
Cys 971 | Leu 971 | engineered mutation |
Gly 1070 | Cys 1070 | engineered mutation |
Arg 1121 | Cys 1121 | engineered mutation |
Val 1223 | Cys 1223 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 139015.5 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 494.6 | |
All* | Total formula weight | 139510.2 |