7ZK2
Crystal Structure of human Brachyury G177D variant in complex with CSC027898502
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | T-box transcription factor T | polymer | 172 | 19655.6 | 1 | UniProt (O15178) Pfam (PF00907) In PDB | Homo sapiens (human) | Brachyury protein,Protein T |
| 2 | A | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 3 | A | N-[4-(2-morpholin-4-yl-1,3-thiazol-4-yl)phenyl]ethanamide | non-polymer | 303.4 | 1 | Chemie (IU4) | |||
| 4 | water | water | 18.0 | 215 | Chemie (HOH) |
Sequence modifications
A: 41 - 211 (UniProt: O15178)
| PDB | External Database | Details |
|---|---|---|
| Gly 40 | - | expression tag |
| Asp 177 | Gly 177 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 19655.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 398.4 | |
| All* | Total formula weight | 20054.0 |
