7ZHZ
Leishmania donovani Glucose 6-Phosphate Dehydrogenase mutant C138S complexed with G6P and NADP(H)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Glucose-6-phosphate 1-dehydrogenase | polymer | 562 | 63391.8 | 2 | UniProt (A2CIL3) Pfam (PF00479) Pfam (PF02781) | Leishmania donovani | |
| 2 | C, J (A, B) | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 2 | Chemie (NDP) | |||
| 3 | D, E, I, K (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 4 | F, G, H, M, N... (A, B) | SULFATE ION | non-polymer | 96.1 | 7 | Chemie (SO4) | |||
| 5 | L (B) | 6-O-phosphono-beta-D-glucopyranose | non-polymer | 260.1 | 1 | Chemie (BG6) | |||
| 6 | Q, R (A, B) | water | water | 18.0 | 25 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 562 (UniProt: A2CIL3)
| PDB | External Database | Details |
|---|---|---|
| Ser 138 | Cys 138 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 126783.6 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 2671.7 | |
| All* | Total formula weight | 129455.3 |
