7ZHQ
Crystal structure of TTBK1 in complex with compound 10 (7-009)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Tau-tubulin kinase 1 | polymer | 309 | 35515.0 | 1 | UniProt (Q5TCY1) Pfam (PF00069) In PDB | Homo sapiens (human) | Brain-derived tau kinase |
| 2 | A | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 3 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 9 | Chemie (EDO) | |||
| 4 | A | (3~{S})-1-(4-azanyl-3,5,12-triazatetracyclo[9.7.0.0^{2,7}.0^{13,18}]octadeca-1(11),2,4,6,13(18),14,16-heptaen-16-yl)-3-methyl-pent-1-yn-3-ol | non-polymer | 346.4 | 1 | Chemie (IRD) | |||
| 5 | water | water | 18.0 | 183 | Chemie (HOH) |
Sequence modifications
A: 13 - 320 (UniProt: Q5TCY1)
| PDB | External Database | Details |
|---|---|---|
| Met 12 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 35515.0 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1000.0 | |
| All* | Total formula weight | 36515.0 |
