7ZHO
Crystal structure of TTBK1 in complex with compound 3 (7-001)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Tau-tubulin kinase 1 | polymer | 309 | 35515.0 | 1 | UniProt (Q5TCY1) Pfam (PF00069) | Homo sapiens (human) | Brain-derived tau kinase |
| 2 | B (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 3 | C, D, E, F (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 4 | G (A) | 4-[3-(2-azanylpyrimidin-4-yl)-1~{H}-indol-5-yl]-2-methyl-but-3-yn-2-ol | non-polymer | 292.3 | 1 | Chemie (IQR) | |||
| 5 | H (A) | water | water | 18.0 | 151 | Chemie (HOH) |
Sequence modifications
A: 13 - 320 (UniProt: Q5TCY1)
| PDB | External Database | Details |
|---|---|---|
| Met 12 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 35515.0 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 635.6 | |
| All* | Total formula weight | 36150.6 |
