7ZHI

Crystal Structure of truncated aspartate transcarbamoylase from Plasmodium falciparum with bound inhibitor indole

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C	Aspartate carbamoyltransferase	polymer	349	40350.8	3	UniProt (A0A5K1K910) Pfam (PF02729) Pfam (PF00185) In PDB	Plasmodium falciparum 3D7
2	A, B	INDOLE	non-polymer		117.1	2	Chemie (IND)
3	A, B	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
4		water	water		18.0	31	Chemie (HOH)

Sequence modifications

A, B, C: 37 - 375 (UniProt: A0A5K1K910)

PDB	External Database	Details
Ser 376	-	expression tag
Ala 377	-	expression tag
Trp 378	-	expression tag
Ser 379	-	expression tag
His 380	-	expression tag
Pro 381	-	expression tag
Gln 382	-	expression tag
Phe 383	-	expression tag
Glu 384	-	expression tag
Lys 385	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	121052.3
Non-Polymers*	Number of molecules	4
	Total formula weight	426.4
All*	Total formula weight	121478.7

*Water molecules are not included.