7ZFD

SARS-CoV-2 Omicron RBD in complex with Omi-25 Fab

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	H, A	Omi-25 heavy chain	polymer	228	24453.5	2		Homo sapiens
2	E, F	Spike protein S1	polymer	209	23880.9	2	UniProt (P0DTC2) Pfam (PF09408) In PDB	Severe acute respiratory syndrome coronavirus 2	SARS-CoV-2 Omicron Spike protein
3	L, B	Omi-25 light chain	polymer	214	23451.0	2		Homo sapiens

Sequence modifications

E, F: 330 - 532 (UniProt: P0DTC2)

PDB	External Database	Details
Asp 339	Gly 339	variant
Leu 371	Ser 371	variant
Pro 373	Ser 373	variant
Phe 375	Ser 375	variant
Asn 417	Lys 417	variant
Lys 440	Asn 440	variant
Ser 446	Gly 446	variant
Asn 477	Ser 477	variant
Lys 478	Thr 478	variant
Ala 484	Glu 484	variant
Arg 493	Gln 493	variant
Ser 496	Gly 496	variant
Arg 498	Gln 498	conflict
Tyr 501	Asn 501	variant
His 505	Tyr 505	variant
His 533	-	expression tag
His 534	-	expression tag
His 535	-	expression tag
His 536	-	expression tag
His 537	-	expression tag
His 538	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	143570.8
All*	Total formula weight	143570.8

*Water molecules are not included.