7ZF1

Structure of ubiquitinated FANCI in complex with FANCD2 and double-stranded DNA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Fanconi anemia group I protein	polymer	1355	152658.6	1	UniProt (Q9NVI1) Pfam (PF14674) Pfam (PF14675) Pfam (PF14679) Pfam (PF14676) Pfam (PF14680) Pfam (PF14677) Pfam (PF14678)	Homo sapiens (human)	Protein FACI
2	B (B)	Fanconi anemia group D2 protein	polymer	1468	166313.7	1	UniProt (Q9BXW9) Pfam (PF14631)	Homo sapiens (human)	Protein FACD2
3	C (C)	Ubiquitin-60S ribosomal protein L40	polymer	80	8875.1	1	UniProt (P62987) Pfam (PF00240)	Homo sapiens (human)	CEP52,Ubiquitin A-52 residue ribosomal protein fusion product 1
4	D (S)	DNA (61-MER)	polymer	29	8951.7	1		synthetic construct
5	E (T)	DNA (61-MER)	polymer	29	8880.7	1		synthetic construct

Sequence modifications

A: 1 - 1328 (UniProt: Q9NVI1)

PDB	External Database	Details
Met -26	-	initiating methionine
His -25	-	expression tag
His -24	-	expression tag
His -23	-	expression tag
His -22	-	expression tag
His -21	-	expression tag
His -20	-	expression tag
Glu -19	-	expression tag
Asn -18	-	expression tag
Leu -17	-	expression tag
Tyr -16	-	expression tag
Phe -15	-	expression tag
Gln -14	-	expression tag
Gly -13	-	expression tag
Lys -12	-	expression tag
Pro -11	-	expression tag
Ile -10	-	expression tag
Pro -9	-	expression tag
Asn -8	-	expression tag
Pro -7	-	expression tag
Leu -6	-	expression tag
Leu -5	-	expression tag
Gly -4	-	expression tag
Leu -3	-	expression tag
Asp -2	-	expression tag
Ser -1	-	expression tag
Thr 0	-	expression tag

B: 1 - 1451 (UniProt: Q9BXW9)

PDB	External Database	Details
Met -16	-	initiating methionine
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Leu -9	-	expression tag
Glu -8	-	expression tag
Val -7	-	expression tag
Leu -6	-	expression tag
Phe -5	-	expression tag
Gln -4	-	expression tag
Gly -3	-	expression tag
Pro -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

C: 1 - 76 (UniProt: P62987)

PDB	External Database	Details
Gly -3	-	expression tag
Pro -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	345679.9
All*	Total formula weight	345679.9

*Water molecules are not included.