7ZEJ
Crystal structure of the human MGC45594 gene product in complex with celecoxib.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Prostaglandin reductase 3 | polymer | 341 | 36250.7 | 2 | UniProt (Q8N4Q0) Pfam (PF08240) Pfam (PF00107) In PDB | Homo sapiens (human) | PRG-3,Zinc-binding alcohol dehydrogenase domain-containing protein 2 |
| 2 | A, B | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 2 | Chemie (NAP) | |||
| 3 | A, B | 4-[5-(4-METHYLPHENYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL]BENZENESULFONAMIDE | non-polymer | 381.4 | 2 | Chemie (CEL) | |||
| 4 | water | water | 18.0 | 169 | Chemie (HOH) |
Sequence modifications
A, B: 24 - 362 (UniProt: Q8N4Q0)
| PDB | External Database | Details |
|---|---|---|
| Ser 22 | - | expression tag |
| Met 23 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 72501.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 2249.6 | |
| All* | Total formula weight | 74751.0 |
