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7ZEH

Human cytosolic 5' nucleotidase IIIB in complex with 3,4-diF-Bn7Guanine

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
7-methylguanosine phosphate-specific 5'-nucleotidasepolymer30234675.74UniProt (Q969T7)
Pfam (PF05822)
Homo sapiens (human)7-methylguanosine nucleotidase,Cytosolic 5'-nucleotidase 3B,Cytosolic 5'-nucleotidase III-like protein,cN-III-like protein,N(7)-methylguanylate 5'-phosphatase
2E, P, PA, Z
(A, B, D, C)
N7-(3,4-difluorobenzyl) guaninenon-polymer278.24Chemie (IPQ)
3AA, F, Q, QA
(C, A, B, D)
D-ribulosenon-polymer150.14Chemie (RBL)
4BA, CA, DA, EA, FA...
(C, A, D, B)
1,2-ETHANEDIOLnon-polymer62.129Chemie (EDO)
5LA, M, W, YA
(C, A, B, D)
MAGNESIUM IONnon-polymer24.34Chemie (MG)
6MA, N, X, ZA
(C, A, B, D)
PHOSPHATE IONnon-polymer95.04Chemie (PO4)
7AB, NA, O, Y
(D, C, A, B)
SULFATE IONnon-polymer96.14Chemie (SO4)
8BB, CB, DB, EB
(A, B, C, D)
waterwater18.01054Chemie (HOH)
Sequence modifications
A, B, C, D: 1 - 300 (UniProt: Q969T7)
PDBExternal DatabaseDetails
Arg -1-expression tag
Ser 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight138702.7
Non-Polymers*Number of molecules49
Total formula weight4374.8
All*Total formula weight143077.5
*Water molecules are not included.

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PDB entries from 2025-11-19

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