7ZDP
Complex I from Ovis aries at pH9, Open state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (4) | Complex I-49kD | polymer | 463 | 52661.5 | 1 | UniProt (A0A7M4DUF9) Pfam (PF00346) UniProt (by SIFTS) (A0A6P3DZ89) | Ovis aries (sheep) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 2,mitochondrial,NADH-ubiquinone oxidoreductase 49 kDa subunit |
| 2 | B (A) | NADH-ubiquinone oxidoreductase chain 3 | polymer | 115 | 13106.5 | 1 | UniProt (O78753) Pfam (PF00507) | Ovis aries (sheep) | NADH dehydrogenase subunit 3 |
| 3 | C (H) | NADH-ubiquinone oxidoreductase chain 1 | polymer | 318 | 35884.9 | 1 | UniProt (O78747) Pfam (PF00146) | Ovis aries (sheep) | NADH dehydrogenase subunit 1 |
| 4 | D (J) | NADH-ubiquinone oxidoreductase chain 6 | polymer | 175 | 19126.6 | 1 | UniProt (O78757) Pfam (PF00499) | Ovis aries (sheep) | NADH dehydrogenase subunit 6 |
| 5 | E (K) | NADH-ubiquinone oxidoreductase chain 4L | polymer | 98 | 10868.2 | 1 | UniProt (O78754) Pfam (PF00420) | Ovis aries (sheep) | NADH dehydrogenase subunit 4L |
| 6 | F (L) | NADH-ubiquinone oxidoreductase chain 5 | polymer | 606 | 68438.9 | 1 | UniProt (O78756) Pfam (PF00662) Pfam (PF00361) Pfam (PF06455) | Ovis aries (sheep) | NADH dehydrogenase subunit 5 |
| 7 | G (M) | NADH-ubiquinone oxidoreductase chain 4 | polymer | 459 | 52086.7 | 1 | UniProt (O78755) Pfam (PF01059) Pfam (PF00361) | Ovis aries (sheep) | NADH dehydrogenase subunit 4 |
| 8 | H (N) | NADH-ubiquinone oxidoreductase chain 2 | polymer | 347 | 39149.8 | 1 | UniProt (O78748) Pfam (PF00361) Pfam (PF06444) | Ovis aries (sheep) | NADH dehydrogenase subunit 2 |
| 9 | I (V) | Complex I-B14.7 | polymer | 140 | 14652.8 | 1 | UniProt (W5PAR2) Pfam (PF02466) UniProt (by SIFTS) (A0A8N7XJ91) | Ovis aries (sheep) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11,NADH-ubiquinone oxidoreductase subunit B14.7 |
| 10 | J (W) | Complex I-SGDH | polymer | 139 | 16317.0 | 1 | UniProt (A0A6P3E6Y9) Pfam (PF09781) UniProt (by SIFTS) (A0A8N7XJ68) | Ovis aries (sheep) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5,mitochondrial,NADH-ubiquinone oxidoreductase SGDH subunit |
| 11 | K, SA (X, j) | Acyl carrier protein | polymer | 157 | 17608.2 | 2 | UniProt (W5NQT7) Pfam (PF00550) | Ovis aries (sheep) | |
| 12 | L (Y) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 | polymer | 171 | 20008.0 | 1 | UniProt (A0A6P3EAP5) Pfam (PF06747) UniProt (by SIFTS) (A0A8N7XJG2) | Ovis aries (sheep) | |
| 13 | M (Z) | Complex I-PDSW | polymer | 171 | 20526.4 | 1 | UniProt (A0A6P3EI17) Pfam (PF10249) | Ovis aries (sheep) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10,NADH-ubiquinone oxidoreductase PDSW subunit |
| 14 | N (k) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial | polymer | 320 | 36883.7 | 1 | UniProt (W5QBF5) Pfam (PF01712) UniProt (by SIFTS) (A0A8N7XJK5) | Ovis aries (sheep) | |
| 15 | O (l) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 | polymer | 105 | 12474.4 | 1 | UniProt (A0A836D7R1) Pfam (PF10200) | Ovis aries (sheep) | Complex I-15 kDa,NADH-ubiquinone oxidoreductase 15 kDa subunit |
| 16 | P (m) | Complex I-B9 | polymer | 80 | 8869.3 | 1 | UniProt (W5NYM7) Pfam (PF14987) UniProt (by SIFTS) (A0A836A4Q3) | Ovis aries (sheep) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3,NADH-ubiquinone oxidoreductase B9 subunit |
| 17 | Q (n) | Complex I-B12 | polymer | 79 | 8958.2 | 1 | UniProt (A0A6P3E8V0) Pfam (PF08122) UniProt (by SIFTS) (A0A6P7DQB1) | Ovis aries (sheep) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3,NADH-ubiquinone oxidoreductase B12 subunit |
| 18 | R (o) | NADH dehydrogenase [ubiquinone] 1 subunit C2 | polymer | 120 | 14231.4 | 1 | UniProt (W5P9Q8) Pfam (PF06374) | Ovis aries (sheep) | |
| 19 | S (p) | NADH:ubiquinone oxidoreductase subunit B4 | polymer | 128 | 14976.0 | 1 | UniProt (W5QF73) Pfam (PF07225) | Ovis aries (sheep) | |
| 20 | T (q) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 | polymer | 144 | 16766.5 | 1 | UniProt (A0A6P3E975) Pfam (PF06212) | Ovis aries (sheep) | |
| 21 | U (r) | Mitochondrial complex I, B17 subunit | polymer | 128 | 15565.1 | 1 | UniProt (W5PZE3) Pfam (PF09782) | Ovis aries (sheep) | |
| 22 | V (s) | Complex I-B18 | polymer | 122 | 14963.1 | 1 | UniProt (W5P5V3) Pfam (PF05676) UniProt (by SIFTS) (A0A8N7XJH2) | Ovis aries (sheep) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7,NADH-ubiquinone oxidoreductase B18 subunit |
| 23 | W (t) | Complex I-B22 | polymer | 177 | 21517.5 | 1 | UniProt (W5PGA3) Pfam (PF05347) UniProt (by SIFTS) (A0A6P3E749) | Ovis aries (sheep) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9,NADH-ubiquinone oxidoreductase B22 subunit |
| 24 | X (u) | Complex I-AGGG | polymer | 65 | 7898.8 | 1 | UniProt (A0A6P3EC72) Pfam (PF14813) UniProt (by SIFTS) (A0A8N7XJB4) | Ovis aries (sheep) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2,mitochondrial,NADH-ubiquinone oxidoreductase AGGG subunit |
| 25 | Y (v) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial | polymer | 155 | 18521.8 | 1 | UniProt (W5Q1B0) Pfam (PF05821) | Ovis aries (sheep) | Complex I-ASHI,NADH-ubiquinone oxidoreductase ASHI subunit |
| 26 | Z (w) | Complex I-ESSS | polymer | 101 | 11998.4 | 1 | UniProt (A0A836CQA7) Pfam (PF10183) | Ovis aries (sheep) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11,mitochondrial,NADH-ubiquinone oxidoreductase ESSS subunit |
| 27 | AA (x) | Complex I-KFYI | polymer | 49 | 5808.6 | 1 | UniProt (A0A6P3EDV0) Pfam (PF15088) | Ovis aries (sheep) | NADH dehydrogenase [ubiquinone] 1 subunit C1,mitochondrial,NADH-ubiquinone oxidoreductase KFYI subunit |
| 28 | BA (y) | Complex I-MNLL | polymer | 50 | 6146.1 | 1 | UniProt (A0A7M4DUG1) Pfam (PF08040) | Ovis aries (sheep) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1,NADH-ubiquinone oxidoreductase MNLL subunit |
| 29 | CA (z) | Complex I-MWFE | polymer | 70 | 8211.5 | 1 | UniProt (A0A7M4DUG2) Pfam (PF15879) UniProt (by SIFTS) (A0A6P9FRJ5) | Ovis aries (sheep) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1,NADH-ubiquinone oxidoreductase MWFE subunit |
| 30 | DA (1) | NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial | polymer | 430 | 47186.7 | 1 | UniProt (A0A835ZPN7) Pfam (PF01512) Pfam (PF22461) Pfam (PF10589) UniProt (by SIFTS) (W5PUX0) | Ovis aries (sheep) | |
| 31 | EA (2) | NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial | polymer | 213 | 23598.2 | 1 | UniProt (W5NRY1) Pfam (PF01257) | Ovis aries (sheep) | NADH-ubiquinone oxidoreductase 24 kDa subunit |
| 32 | FA (3) | NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial | polymer | 688 | 75520.5 | 1 | UniProt (W5QB34) Pfam (PF09326) Pfam (PF13510) Pfam (PF10588) Pfam (PF22117) Pfam (PF22151) Pfam (PF00384) UniProt (by SIFTS) (A0A9J4RF63) | Ovis aries (sheep) | |
| 33 | GA (5) | Complex I-30kD | polymer | 208 | 24381.5 | 1 | UniProt (A0A6P3EKX5) Pfam (PF00329) UniProt (by SIFTS) (W5PB27) | Ovis aries (sheep) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 3,mitochondrial,NADH-ubiquinone oxidoreductase 30 kDa subunit |
| 34 | HA (6) | Complex I-20kD | polymer | 156 | 17861.0 | 1 | UniProt (A0A6P7E4I4) Pfam (PF01058) UniProt (by SIFTS) (A0A6P7E5N1) | Ovis aries (sheep) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 7,mitochondrial,NADH-ubiquinone oxidoreductase 20 kDa subunit |
| 35 | IA (9) | Complex I-23kD | polymer | 176 | 20219.9 | 1 | UniProt (A0A6P3TFB2) Pfam (PF12838) | Ovis aries (sheep) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 8,mitochondrial,NADH-ubiquinone oxidoreductase 23 kDa subunit |
| 36 | JA (a) | Complex I-9kD | polymer | 44 | 5263.8 | 1 | UniProt (A0A836AFZ8) Pfam (PF15880) UniProt (by SIFTS) (A0A6P3E7B5) | Ovis aries (sheep) | NADH dehydrogenase [ubiquinone] flavoprotein 3,mitochondrial,NADH-ubiquinone oxidoreductase 9 kDa subunit |
| 37 | KA (b) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial | polymer | 95 | 10513.6 | 1 | UniProt (A0A6P7EX23) Pfam (PF10276) | Ovis aries (sheep) | |
| 38 | LA (c) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial | polymer | 126 | 14559.5 | 1 | UniProt (W5PE07) Pfam (PF04800) | Ovis aries (sheep) | Complex I-18 kDa,NADH-ubiquinone oxidoreductase 18 kDa subunit |
| 39 | MA (d) | NADH:ubiquinone oxidoreductase subunit A9 | polymer | 380 | 43025.6 | 1 | UniProt (W5PI58) Pfam (PF01370) UniProt (by SIFTS) (A0A6P3E3I5) | Ovis aries (sheep) | |
| 40 | NA (e) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 | polymer | 86 | 9841.3 | 1 | UniProt (W5QAH8) Pfam (PF05047) UniProt (by SIFTS) (A0A8N7XJ49) | Ovis aries (sheep) | |
| 41 | OA (f) | Complex I subunit B13 | polymer | 113 | 13028.2 | 1 | UniProt (W5PNX7) Pfam (PF04716) UniProt (by SIFTS) (W5NRE6) | Ovis aries (sheep) | Complex I-13kD-B,NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5,NADH-ubiquinone oxidoreductase 13 kDa-B subunit |
| 42 | PA (g) | Complex I-B14 | polymer | 114 | 13768.0 | 1 | UniProt (W5QC06) Pfam (PF05347) | Ovis aries (sheep) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6,NADH-ubiquinone oxidoreductase B14 subunit |
| 43 | QA (h) | Mitochondrial complex I, B14.5a subunit | polymer | 114 | 12701.6 | 1 | UniProt (W5P0I2) Pfam (PF07347) | Ovis aries (sheep) | |
| 44 | RA (i) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 | polymer | 145 | 17115.5 | 1 | UniProt (A0A6P3CXE3) Pfam (PF05071) UniProt (by SIFTS) (A0A8N7XJ18) | Ovis aries (sheep) | |
| 45 | JB, TA (j, X) | S-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate | non-polymer | 568.7 | 2 | Chemie (ZMP) | |||
| 46 | UA (k) | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 1 | Chemie (AMP) | |||
| 47 | VA (s) | MYRISTIC ACID | non-polymer | 228.4 | 1 | Chemie (MYR) | |||
| 48 | AB, BB, EB, FB, GB... (3, 6, 9, 1) | IRON/SULFUR CLUSTER | non-polymer | 351.6 | 6 | Chemie (SF4) | |||
| 49 | XA (1) | FLAVIN MONONUCLEOTIDE | non-polymer | 456.3 | 1 | Chemie (FMN) | |||
| 50 | YA (1) | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE | non-polymer | 665.4 | 1 | Chemie (NAI) | |||
| 51 | CB, ZA (3, 2) | FE2/S2 (INORGANIC) CLUSTER | non-polymer | 175.8 | 2 | Chemie (FES) | |||
| 52 | DB (3) | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) | |||
| 53 | HB (b) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 54 | IB (d) | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 1 | Chemie (NDP) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 45 |
| Total formula weight | 970419.0 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 6146.2 | |
| All* | Total formula weight | 976565.2 |
