7ZDN
Human Cyclophilin D in complex with fragment
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Peptidyl-prolyl cis-trans isomerase F, mitochondrial | polymer | 165 | 17782.3 | 2 | UniProt (P30405) Pfam (PF00160) In PDB | Homo sapiens (human) | PPIase F,Cyclophilin D,CypD,Cyclophilin F,Mitochondrial cyclophilin,CyP-M,Rotamase F, Human Cyclophilin D |
| 2 | A, B | (1~{R},9~{R},10~{S})-12-oxa-8-azatricyclo[7.3.1.0^{2,7}]trideca-2(7),3,5-trien-10-ol | non-polymer | 191.2 | 2 | Chemie (IU0) | |||
| 3 | water | water | 18.0 | 444 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 165 (UniProt: P30405)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
| Gln 125 | Lys 167 | engineered mutation |
| Ile 133 | Lys 175 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 35564.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 382.5 | |
| All* | Total formula weight | 35947.0 |
