7ZDJ
Complex I from Ovis aries at pH5.5, Open state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (4) | Complex I-49kD | polymer | 463 | 52661.5 | 1 | UniProt (A0A7M4DUF9) UniProt (by SIFTS) (A0A6P3DZ89) | Ovis aries (sheep) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 2,mitochondrial,NADH-ubiquinone oxidoreductase 49 kDa subunit |
| 2 | B (A) | NADH-ubiquinone oxidoreductase chain 3 | polymer | 115 | 13106.5 | 1 | UniProt (O78753) Pfam (PF00507) | Ovis aries (sheep) | NADH dehydrogenase subunit 3 |
| 3 | C (H) | NADH-ubiquinone oxidoreductase chain 1 | polymer | 318 | 35884.9 | 1 | UniProt (O78747) Pfam (PF00146) | Ovis aries (sheep) | NADH dehydrogenase subunit 1 |
| 4 | D (J) | NADH-ubiquinone oxidoreductase chain 6 | polymer | 175 | 19126.6 | 1 | UniProt (O78757) Pfam (PF00499) | Ovis aries (sheep) | NADH dehydrogenase subunit 6 |
| 5 | E (K) | NADH-ubiquinone oxidoreductase chain 4L | polymer | 98 | 10868.2 | 1 | UniProt (O78754) Pfam (PF00420) | Ovis aries (sheep) | NADH dehydrogenase subunit 4L |
| 6 | F (L) | NADH-ubiquinone oxidoreductase chain 5 | polymer | 606 | 68438.9 | 1 | UniProt (O78756) Pfam (PF00662) Pfam (PF00361) Pfam (PF06455) | Ovis aries (sheep) | NADH dehydrogenase subunit 5 |
| 7 | G (M) | NADH-ubiquinone oxidoreductase chain 4 | polymer | 459 | 52086.7 | 1 | UniProt (O78755) Pfam (PF01059) Pfam (PF00361) | Ovis aries (sheep) | NADH dehydrogenase subunit 4 |
| 8 | H (N) | NADH-ubiquinone oxidoreductase chain 2 | polymer | 347 | 39149.8 | 1 | UniProt (O78748) Pfam (PF00361) Pfam (PF06444) | Ovis aries (sheep) | NADH dehydrogenase subunit 2 |
| 9 | I (V) | Complex I-B14.7 | polymer | 140 | 14652.8 | 1 | UniProt (A0A6P3E4K7) UniProt (by SIFTS) (A0A8N7XJ91) | Ovis aries (sheep) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11,NADH-ubiquinone oxidoreductase subunit B14.7 |
| 10 | J (W) | Complex I-SGDH | polymer | 139 | 16317.0 | 1 | UniProt (A0A6P3E6Y9) UniProt (by SIFTS) (A0A8N7XJ68) | Ovis aries (sheep) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5,mitochondrial,NADH-ubiquinone oxidoreductase SGDH subunit |
| 11 | K, SA (X, j) | Acyl carrier protein | polymer | 157 | 17608.2 | 2 | UniProt (W5NQT7) | Ovis aries (sheep) | |
| 12 | L (Y) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 | polymer | 171 | 20008.0 | 1 | UniProt (A0A6P3EAP5) UniProt (by SIFTS) (A0A8N7XJG2) | Ovis aries (sheep) | |
| 13 | M (Z) | Complex I-PDSW | polymer | 171 | 20526.4 | 1 | UniProt (A0A6P3EI17) | Ovis aries (sheep) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10,NADH-ubiquinone oxidoreductase PDSW subunit |
| 14 | N (k) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial | polymer | 320 | 36883.7 | 1 | UniProt (W5QBF5) UniProt (by SIFTS) (A0A8N7XJK5) | Ovis aries (sheep) | |
| 15 | O (l) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 | polymer | 105 | 12474.4 | 1 | UniProt (A0A836D7R1) | Ovis aries (sheep) | Complex I-15 kDa,NADH-ubiquinone oxidoreductase 15 kDa subunit |
| 16 | P (m) | Complex I-B9 | polymer | 80 | 8869.3 | 1 | UniProt (W5NYM7) UniProt (by SIFTS) (A0A836A4Q3) | Ovis aries (sheep) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3,NADH-ubiquinone oxidoreductase B9 subunit |
| 17 | Q (n) | Complex I-B12 | polymer | 79 | 8958.2 | 1 | UniProt (A0A6P3E8V0) UniProt (by SIFTS) (A0A6P7DQB1) | Ovis aries (sheep) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3,NADH-ubiquinone oxidoreductase B12 subunit |
| 18 | R (o) | NADH dehydrogenase [ubiquinone] 1 subunit C2 | polymer | 120 | 14231.4 | 1 | UniProt (W5P9Q8) | Ovis aries (sheep) | |
| 19 | S (p) | NADH:ubiquinone oxidoreductase subunit B4 | polymer | 128 | 14976.0 | 1 | UniProt (W5QF73) | Ovis aries (sheep) | |
| 20 | T (q) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 | polymer | 144 | 16766.5 | 1 | UniProt (A0A6P3E975) | Ovis aries (sheep) | |
| 21 | U (r) | Mitochondrial complex I, B17 subunit | polymer | 128 | 15565.1 | 1 | UniProt (W5PZE3) | Ovis aries (sheep) | |
| 22 | V (s) | Complex I-B18 | polymer | 122 | 14963.1 | 1 | UniProt (W5P5V3) UniProt (by SIFTS) (A0A8N7XJH2) | Ovis aries (sheep) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7,NADH-ubiquinone oxidoreductase B18 subunit |
| 23 | W (t) | Complex I-B22 | polymer | 177 | 21517.5 | 1 | UniProt (W5PGA3) UniProt (by SIFTS) (A0A6P3E749) | Ovis aries (sheep) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9,NADH-ubiquinone oxidoreductase B22 subunit |
| 24 | X (u) | Complex I-AGGG | polymer | 65 | 7898.8 | 1 | UniProt (W5PVD7) UniProt (by SIFTS) (A0A8N7XJB4) | Ovis aries (sheep) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2,mitochondrial,NADH-ubiquinone oxidoreductase AGGG subunit |
| 25 | Y (v) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial | polymer | 155 | 18521.8 | 1 | UniProt (W5Q1B0) | Ovis aries (sheep) | Complex I-ASHI,NADH-ubiquinone oxidoreductase ASHI subunit |
| 26 | Z (w) | Complex I-ESSS | polymer | 101 | 11998.4 | 1 | UniProt (A0A836CQA7) | Ovis aries (sheep) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11,mitochondrial,NADH-ubiquinone oxidoreductase ESSS subunit |
| 27 | AA (x) | Complex I-KFYI | polymer | 49 | 5808.6 | 1 | UniProt (A0A6P3EDV0) | Ovis aries (sheep) | NADH dehydrogenase [ubiquinone] 1 subunit C1,mitochondrial,NADH-ubiquinone oxidoreductase KFYI subunit |
| 28 | BA (y) | Complex I-MNLL | polymer | 50 | 6146.1 | 1 | UniProt (A0A7M4DUG1) | Ovis aries (sheep) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1,NADH-ubiquinone oxidoreductase MNLL subunit |
| 29 | CA (z) | Complex I-MWFE | polymer | 70 | 8211.5 | 1 | UniProt (A0A7M4DUG2) UniProt (by SIFTS) (A0A6P9FRJ5) | Ovis aries (sheep) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1,NADH-ubiquinone oxidoreductase MWFE subunit |
| 30 | DA (1) | NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial | polymer | 430 | 47186.7 | 1 | UniProt (A0A835ZPN7) | Ovis aries (sheep) | |
| 31 | EA (2) | NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial | polymer | 213 | 23598.2 | 1 | UniProt (W5NRY1) | Ovis aries (sheep) | NADH-ubiquinone oxidoreductase 24 kDa subunit |
| 32 | FA (3) | NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial | polymer | 688 | 75520.5 | 1 | UniProt (W5QB34) UniProt (by SIFTS) (A0A9J4RF63) | Ovis aries (sheep) | |
| 33 | GA (5) | Complex I-30kD | polymer | 208 | 24381.5 | 1 | UniProt (A0A6P3EKX5) | Ovis aries (sheep) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 3,mitochondrial,NADH-ubiquinone oxidoreductase 30 kDa subunit |
| 34 | HA (6) | Complex I-20kD | polymer | 156 | 17861.0 | 1 | UniProt (A0A6P7E4I4) UniProt (by SIFTS) (A0A6P7E5N1) | Ovis aries (sheep) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 7,mitochondrial,NADH-ubiquinone oxidoreductase 20 kDa subunit |
| 35 | IA (9) | Complex I-23kD | polymer | 176 | 20219.9 | 1 | UniProt (A0A6P3TFB2) | Ovis aries (sheep) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 8,mitochondrial,NADH-ubiquinone oxidoreductase 23 kDa subunit |
| 36 | JA (a) | Complex I-9kD | polymer | 44 | 5263.8 | 1 | UniProt (A0A836AFZ8) UniProt (by SIFTS) (A0A6P3E7B5) | Ovis aries (sheep) | NADH dehydrogenase [ubiquinone] flavoprotein 3,mitochondrial,NADH-ubiquinone oxidoreductase 9 kDa subunit |
| 37 | KA (b) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial | polymer | 95 | 10513.6 | 1 | UniProt (A0A6P7EX23) | Ovis aries (sheep) | |
| 38 | LA (c) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial | polymer | 126 | 14559.5 | 1 | UniProt (W5PE07) | Ovis aries (sheep) | Complex I-18 kDa,NADH-ubiquinone oxidoreductase 18 kDa subunit |
| 39 | MA (d) | NADH:ubiquinone oxidoreductase subunit A9 | polymer | 380 | 43025.6 | 1 | UniProt (W5PI58) UniProt (by SIFTS) (A0A6P3E3I5) | Ovis aries (sheep) | |
| 40 | NA (e) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 | polymer | 86 | 9841.3 | 1 | UniProt (A0A6P3E5Z9) UniProt (by SIFTS) (A0A8N7XJ49) | Ovis aries (sheep) | |
| 41 | OA (f) | Complex I subunit B13 | polymer | 113 | 13028.2 | 1 | UniProt (W5PNX7) UniProt (by SIFTS) (A0A836ABR5) | Ovis aries (sheep) | Complex I-13kD-B,NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5,NADH-ubiquinone oxidoreductase 13 kDa-B subunit |
| 42 | PA (g) | Complex I-B14 | polymer | 114 | 13768.0 | 1 | UniProt (W5QC06) | Ovis aries (sheep) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6,NADH-ubiquinone oxidoreductase B14 subunit |
| 43 | QA (h) | Mitochondrial complex I, B14.5a subunit | polymer | 114 | 12701.6 | 1 | UniProt (W5P0I2) | Ovis aries (sheep) | |
| 44 | RA (i) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 | polymer | 145 | 17115.5 | 1 | UniProt (A0A6P3CXE3) UniProt (by SIFTS) (A0A8N7XJ18) | Ovis aries (sheep) | |
| 45 | IB, TA (j, X) | S-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate | non-polymer | 568.7 | 2 | Chemie (ZMP) PubChem (24941266) PubChem (74369227) PubChem (119058172) | |||
| 46 | UA (s) | MYRISTIC ACID | non-polymer | 228.4 | 1 | Chemie (MYR) PubChem (11005) | |||
| 47 | AB, DB, EB, FB, VA... (3, 6, 9, 1) | IRON/SULFUR CLUSTER | non-polymer | 351.6 | 6 | Chemie (SF4) | |||
| 48 | WA (1) | FLAVIN MONONUCLEOTIDE | non-polymer | 456.3 | 1 | Chemie (FMN) PubChem (710) PubChem (8965) PubChem (643976) PubChem (5702760) PubChem (7048779) PubChem (7048781) PubChem (23585816) PubChem (51435500) PubChem (51435503) PubChem (15559251) | |||
| 49 | XA (1) | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE | non-polymer | 665.4 | 1 | Chemie (NAI) PubChem (928) PubChem (11250888) PubChem (12309341) PubChem (16219774) PubChem (44119956) PubChem (44415182) PubChem (439153) PubChem (124934832) PubChem (126455899) PubChem (134693949) PubChem (12309339) PubChem (12309347) PubChem (140875346) PubChem (162951601) PubChem (162951600) PubChem (164575491) PubChem (169545638) PubChem (170905224) PubChem (174316169) PubChem (94865921) PubChem (94865923) PubChem (124432988) PubChem (124934831) PubChem (124934833) PubChem (129607000) PubChem (129628338) PubChem (146167236) PubChem (162951602) PubChem (174084875) | |||
| 50 | BB, YA (3, 2) | FE2/S2 (INORGANIC) CLUSTER | non-polymer | 175.8 | 2 | Chemie (FES) | |||
| 51 | CB (3) | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) PubChem (813) | |||
| 52 | GB (b) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 53 | HB (d) | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 1 | Chemie (NDP) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 45 |
| Total formula weight | 970419.0 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 5799.0 | |
| All* | Total formula weight | 976218.0 |
