7ZB8
Crystal Structure of SARS-CoV-2 Main Protease (Mpro) variant K61A at 2.48 A resolution
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | 3C-like proteinase nsp5 | polymer | 306 | 33767.4 | 2 | UniProt (P0DTD1) Pfam (PF05409) In PDB | Severe acute respiratory syndrome coronavirus 2 | 3CL-PRO,3CLp,Main protease,Mpro,Non-structural protein 5,nsp5,SARS coronavirus main proteinase |
2 | C | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 4 | Chemie (DMS) | |||
3 | water | water | 18.0 | 36 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 306 (UniProt: P0DTD1)
PDB | External Database | Details |
---|---|---|
Ala 61 | Lys 3324 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 67534.9 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 312.5 | |
All* | Total formula weight | 67847.4 |