7Z93
Crystal structure of YTHDF2 with compound YLI_DF_022
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | YTH domain-containing family protein 2 | polymer | 167 | 19367.8 | 2 | UniProt (Q9Y5A9) Pfam (PF04146) In PDB | Homo sapiens (human) | CLL-associated antigen KW-14,High-glucose-regulated protein 8,Renal carcinoma antigen NY-REN-2 |
2 | A | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
3 | A, B | SULFATE ION | non-polymer | 96.1 | 6 | Chemie (SO4) | |||
4 | A, B | 5-azanyl-6-ethyl-1H-pyrimidine-2,4-dione | non-polymer | 155.2 | 2 | Chemie (IHF) | |||
5 | water | water | 18.0 | 82 | Chemie (HOH) |
Sequence modifications
A, B: 408 - 552 (UniProt: Q9Y5A9)
PDB | External Database | Details |
---|---|---|
Met 386 | - | initiating methionine |
Gly 387 | - | expression tag |
Ser 388 | - | expression tag |
Ser 389 | - | expression tag |
Tyr 390 | - | expression tag |
His 391 | - | expression tag |
His 392 | - | expression tag |
His 393 | - | expression tag |
His 394 | - | expression tag |
His 395 | - | expression tag |
His 396 | - | expression tag |
Ser 397 | - | expression tag |
Ser 398 | - | expression tag |
Gly 399 | - | expression tag |
Glu 400 | - | expression tag |
Asn 401 | - | expression tag |
Leu 402 | - | expression tag |
Tyr 403 | - | expression tag |
Phe 404 | - | expression tag |
Gln 405 | - | expression tag |
His 406 | - | expression tag |
Met 407 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 38735.7 | |
Non-Polymers* | Number of molecules | 10 |
Total formula weight | 957.6 | |
All* | Total formula weight | 39693.3 |