7Z87
DNA-PK in the active state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | DNA-dependent protein kinase catalytic subunit | polymer | 4128 | 469673.2 | 1 | UniProt (P78527) Pfam (PF20502) Pfam (PF08163) Pfam (PF19704) Pfam (PF02259) Pfam (PF00454) Pfam (PF02260) In PDB | Homo sapiens (human) | DNA-PK catalytic subunit,DNA-PKcs,DNPK1,p460 |
| 2 | B | X-ray repair cross-complementing protein 6 | polymer | 609 | 69945.0 | 1 | UniProt (P12956) Pfam (PF02037) Pfam (PF03731) Pfam (PF02735) Pfam (PF03730) In PDB | Homo sapiens (human) | 5'-deoxyribose-5-phosphate lyase Ku70,5'-dRP lyase Ku70,70 kDa subunit of Ku antigen,ATP-dependent DNA helicase 2 subunit 1,ATP-dependent DNA helicase II 70 kDa subunit,CTC box-binding factor 75 kDa subunit,CTCBF,DNA repair protein XRCC6,Lupus Ku autoantigen protein p70,Ku70,Thyroid-lupus autoantigen,TLAA,X-ray repair complementing defective repair in Chinese hamster cells 6 |
| 3 | C | X-ray repair cross-complementing protein 5 | polymer | 732 | 82812.4 | 1 | UniProt (P13010) Pfam (PF03731) Pfam (PF02735) Pfam (PF03730) Pfam (PF08785) In PDB | Homo sapiens (human) | 86 kDa subunit of Ku antigen,ATP-dependent DNA helicase 2 subunit 2,ATP-dependent DNA helicase II 80 kDa subunit,CTC box-binding factor 85 kDa subunit,CTCBF,DNA repair protein XRCC5,Ku80,Ku86,Lupus Ku autoantigen protein p86,Nuclear factor IV,Thyroid-lupus autoantigen,TLAA,X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) |
| 4 | D | DNA (26-MER) | polymer | 26 | 7900.1 | 1 | Homo sapiens | ||
| 5 | E | DNA (26-MER) | polymer | 26 | 8078.2 | 1 | Homo sapiens | ||
| 6 | A | (~{S})-[2-chloranyl-4-fluoranyl-5-(7-morpholin-4-ylquinazolin-4-yl)phenyl]-(6-methoxypyridazin-3-yl)methanol | non-polymer | 481.9 | 1 | Chemie (1IX) | |||
| 7 | water | water | 18.0 | 194 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 638409.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 481.9 | |
| All* | Total formula weight | 638890.9 |
