7Z6I
Crystal structure of p38alpha C162S in complex with SB20358 and CAS 2094667-81-7 (behind catalytic site; Y35 in), P 21 21 21
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | AAA | Mitogen-activated protein kinase 14 | polymer | 360 | 41363.1 | 1 | UniProt (P47811) Pfam (PF00069) In PDB | Mus musculus (house mouse) | MAP kinase 14,MAPK 14,CRK1,Mitogen-activated protein kinase p38 alpha,MAP kinase p38 alpha |
| 2 | AAA | 4-[4-(4-fluorophenyl)-2-[4-[methyl(oxidanyl)-$l^{3}-sulfanyl]phenyl]-1~{H}-imidazol-5-yl]pyridine | non-polymer | 377.4 | 1 | Chemie (IIM) | |||
| 3 | AAA | N-(2-cyclobutyl-1H-1,3-benzodiazol-5-yl)benzenesulfonamide | non-polymer | 327.4 | 1 | Chemie (87B) | |||
| 4 | water | water | 18.0 | 200 | Chemie (HOH) |
Sequence modifications
AAA: 1 - 359 (UniProt: P47811)
| PDB | External Database | Details |
|---|---|---|
| Ser 162 | Cys 162 | engineered mutation |
| Gln 360 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 41363.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 704.8 | |
| All* | Total formula weight | 42068.0 |
