7Z53
Structure of native leukocyte myeloperoxidase in complex with a truncated version (SPIN truncated) of the Staphyloccal Peroxidase Inhibitor SPIN from Staphylococcus aureus
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, G, I, M... (A, C, G, I, M...) | Myeloperoxidase light chain | polymer | 106 | 12075.5 | 8 | UniProt (P05164) | Homo sapiens (human) | |
| 2 | B, D, H, J, N... (B, D, H, J, N...) | Myeloperoxidase heavy chain | polymer | 466 | 53234.2 | 8 | UniProt (P05164) Pfam (PF03098) | Homo sapiens (human) | |
| 3 | E, F, K, L, Q... (E, F, K, L, Q...) | Myeloperoxidase inhibitor SPIN | polymer | 59 | 6793.5 | 8 | UniProt (A0A8E8QUP3) UniProt (by SIFTS) (Q2G0X2) | Staphylococcus aureus | |
| 4 | FA, LA, RA, Y (f, l, r, Y) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 4 | In PDB GlyTouCan (G15407YE) | |||
| 5 | Z (Z) | alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G22573RC) | |||
| 6 | AA, CA, EA, HA, KA... (a, c, e, h, k...) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1057.0 | 7 | In PDB GlyTouCan (G82348BZ) | |||
| 7 | BA, DA, GA, MA, OA... (b, d, g, m, o...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 7 | In PDB GlyTouCan (G42666HT) | |||
| 8 | IA (i) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G81315DD) | |||
| 9 | JA (j) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G22768VO) | |||
| 10 | QA (q) | alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 894.8 | 1 | In PDB GlyTouCan (G00395TQ) | |||
| 11 | EB, IB, LB, OB, TB... (G, I, M, O, S...) | CHLORIDE ION | non-polymer | 35.5 | 8 | Chemie (CL) PubChem (312) | |||
| 12 | FB, JB, MB, PB, UB... (G, I, M, O, S...) | HEME C | non-polymer | 620.5 | 8 | Chemie (HEC) | |||
| 13 | AB, GB, KB, NB, QB... (D, H, J, N, P...) | CALCIUM ION | non-polymer | 40.1 | 8 | Chemie (CA) PubChem (271) | |||
| 14 | XA (B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 15 | BB, CB, HB, RB (D, H, P) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) PubChem (24139) | |||
| 16 | DB (D) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) PubChem (175) | |||
| 17 | SB (P) | OXALATE ION | non-polymer | 88.0 | 1 | Chemie (OXL) PubChem (71081) | |||
| 18 | ZB (o) | beta-D-mannopyranose | non-polymer | 180.2 | 1 | Chemie (BMA) PubChem (439680) | |||
| 19 | AC (q) | alpha-D-mannopyranose | non-polymer | 180.2 | 1 | Chemie (MAN) PubChem (185698) | |||
| 20 | BC, CC, DC, EC, FC... (A, B, C, D, E...) | water | water | 18.0 | 1068 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 24 |
| Total formula weight | 576826.0 | |
| Branched | Number of molecules | 22 |
| Total formula weight | 16018.7 | |
| Non-Polymers* | Number of molecules | 33 |
| Total formula weight | 7022.7 | |
| All* | Total formula weight | 599867.4 |
