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7Z4V

Structure of Serine-Threonine kinase STK25 in complex with compound

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Serine/threonine-protein kinase 25polymer29733917.71UniProt (O00506)
Pfam (PF00069)
Homo sapiens (human)Ste20-like kinase,Sterile 20/oxidant stress-response kinase 1,SOK-1,Ste20/oxidant stress response kinase 1
2B
(A)
~{N}-(5-~{tert}-butyl-1~{H}-pyrazol-3-yl)-4-pyrrolidin-1-ylsulfonyl-benzamidenon-polymer376.51Chemie (IB5)
3C
(A)
1,2-ETHANEDIOLnon-polymer62.11Chemie (EDO)
4D
(A)
waterwater18.0162Chemie (HOH)
Sequence modifications
A: 1 - 294 (UniProt: O00506)
PDBExternal DatabaseDetails
Gly -1-expression tag
Ser 0-expression tag
Ser 295-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight33917.7
Non-Polymers*Number of molecules2
Total formula weight438.5
All*Total formula weight34356.3
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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