7Z36
Crystal structure of the KAP1 tripartite motif in complex with the ZNF93 KRAB domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Endolysin,Transcription intermediary factor 1-beta,Isoform 2 of Transcription intermediary factor 1-beta | polymer | 482 | 54755.5 | 2 | UniProt (P00720) UniProt (Q13263) UniProt (Q13263-2) Pfam (PF00959) Pfam (PF14634) Pfam (PF00643) | Homo sapiens (human) | Lysis protein,Lysozyme,Muramidase,TIF1-beta,E3 SUMO-protein ligase TRIM28,KRAB-associated protein 1,KAP-1,KRAB-interacting protein 1,KRIP-1,Nuclear corepressor KAP-1,RING finger protein 96,RING-type E3 ubiquitin transferase TIF1-beta,Tripartite motif-containing protein 28 |
| 2 | C, E (C, S) | SMARCAD1 CUE1 domain | polymer | 73 | 8189.1 | 2 | UniProt (by SIFTS) (Q9H4L7) | Homo sapiens | |
| 3 | D (D) | Zinc finger protein 93 | polymer | 70 | 8194.5 | 1 | UniProt (P35789) Pfam (PF01352) | Homo sapiens (human) | Zinc finger protein 505,Zinc finger protein HTF34 |
| 4 | F, G, H, I, J... (A, B) | ZINC ION | non-polymer | 65.4 | 8 | Chemie (ZN) |
Sequence modifications
A, B: 26 - 185 (UniProt: P00720)
A, B: 187 - 271 (UniProt: Q13263)
A, B: 272 - 482 (UniProt: Q13263-2)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
| Gly 2 | - | expression tag |
| Ser 3 | - | expression tag |
| Ser 4 | - | expression tag |
| His 5 | - | expression tag |
| His 6 | - | expression tag |
| His 7 | - | expression tag |
| His 8 | - | expression tag |
| His 9 | - | expression tag |
| His 10 | - | expression tag |
| Ser 11 | - | expression tag |
| Gln 12 | - | expression tag |
| Asp 13 | - | expression tag |
| Pro 14 | - | expression tag |
| Asn 15 | - | expression tag |
| Ser 16 | - | expression tag |
| Ser 17 | - | expression tag |
| Ser 18 | - | expression tag |
| Glu 19 | - | expression tag |
| Asn 20 | - | expression tag |
| Leu 21 | - | expression tag |
| Tyr 22 | - | expression tag |
| Phe 23 | - | expression tag |
| Gln 24 | - | expression tag |
| Gly 25 | - | expression tag |
| Ala 186 | - | linker |
A, B: 272 - 482 (UniProt: Q13263-2)
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 134083.6 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 523.3 | |
| All* | Total formula weight | 134606.9 |
