7Z2O
PARP15 catalytic domain in complex with OUL215
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Protein mono-ADP-ribosyltransferase PARP15 | polymer | 221 | 25439.5 | 2 | UniProt (Q460N3) Pfam (PF00644) | Homo sapiens (human) | ADP-ribosyltransferase diphtheria toxin-like 7,ARTD7,B-aggressive lymphoma protein 3,Poly [ADP-ribose] polymerase 15,PARP-15 |
| 2 | C (A) | 8-methoxy-[1,2,4]triazolo[3,4-b][1,3]benzothiazole | non-polymer | 205.2 | 1 | Chemie (IAJ) | |||
| 3 | D (B) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 4 | E, F (A, B) | water | water | 18.0 | 288 | Chemie (HOH) |
Sequence modifications
A, B: 481 - 678 (UniProt: Q460N3)
| PDB | External Database | Details |
|---|---|---|
| Met 458 | - | initiating methionine |
| His 459 | - | expression tag |
| His 460 | - | expression tag |
| His 461 | - | expression tag |
| His 462 | - | expression tag |
| His 463 | - | expression tag |
| His 464 | - | expression tag |
| Ser 465 | - | expression tag |
| Ser 466 | - | expression tag |
| Gly 467 | - | expression tag |
| Val 468 | - | expression tag |
| Asp 469 | - | expression tag |
| Leu 470 | - | expression tag |
| Gly 471 | - | expression tag |
| Thr 472 | - | expression tag |
| Glu 473 | - | expression tag |
| Asn 474 | - | expression tag |
| Leu 475 | - | expression tag |
| Tyr 476 | - | expression tag |
| Phe 477 | - | expression tag |
| Gln 478 | - | expression tag |
| Ser 479 | - | expression tag |
| Met 480 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 50878.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 283.4 | |
| All* | Total formula weight | 51162.3 |
