7YZH
Schistosoma Mansoni Carbonic Anhydrase in complex with 4-oxo-N-(4-sulfamoylphenethyl)-1,3,4,6,7,11b-hexahydro-2H-pyrazino[2,1-a]isoquinoline-2-carbothioamide
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (AAA, BBB) | Carbonic anhydrase | polymer | 323 | 36988.0 | 2 | UniProt (A0A3Q0KSG2) Pfam (PF00194) | Schistosoma mansoni | |
| 2 | C, K (AAA, BBB) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D, E, H, I, J (AAA, BBB) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 5 | Chemie (NAG) | |||
| 4 | F, L (AAA, BBB) | 4-oxo-N-(4-sulfamoylphenethyl)-1,3,4,6,7,11b-hexahydro-2H-pyrazino[2,1-a]isoquinoline-2-carbothioamide | non-polymer | 444.6 | 2 | Chemie (HFF) PubChem (166607332) PubChem (166638170) | |||
| 5 | G (BBB) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) PubChem (753) | |||
| 6 | M, N (AAA, BBB) | water | water | 18.0 | 371 | Chemie (HOH) |
Sequence modifications
AAA, BBB: 1 - 323 (UniProt: A0A3Q0KSG2)
| PDB | External Database | Details |
|---|---|---|
| Arg 299 | Ser 299 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 73976.1 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 2218.1 | |
| All* | Total formula weight | 76194.2 |
