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7YYH

Structure of the human CCANdeltaT CENP-A alpha-satellite complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, E
(A, E)
Histone H3-like centromeric protein Apolymer14016023.62UniProt (P49450)
Pfam (PF00125)
Homo sapiens (human)Centromere autoantigen A,Centromere protein A,CENP-A
2B, F
(B, F)
Histone H4polymer10311394.42UniProt (P62805)
Pfam (PF15511)
Homo sapiens (human)
3C, G
(C, G)
Histone H2A type 1-Cpolymer13014135.52UniProt (Q93077)
Pfam (PF00125)
Pfam (PF16211)
Homo sapiens (human)H2A-clustered histone 6,Histone H2A/l
4D, T
(D, h)
Histone H2B type 1-C/E/F/G/Ipolymer12613937.22UniProt (P62807)
Pfam (PF00125)
Homo sapiens (human)Histone H2B.1 A,Histone H2B.a,H2B/a,Histone H2B.g,H2B/g,Histone H2B.h,H2B/h,Histone H2B.k,H2B/k,Histone H2B.l,H2B/l
5H
(H)
Centromere protein Hpolymer24728520.91UniProt (Q9H3R5)
Pfam (PF05837)
Homo sapiens (human)CENP-H,Interphase centromere complex protein 35
6I
(I)
Centromere protein Ipolymer75686820.21UniProt (Q92674)
Pfam (PF07778)
Homo sapiens (human)CENP-I,FSH primary response protein 1,Follicle-stimulating hormone primary response protein,Interphase centromere complex protein 19,Leucine-rich primary response protein 1
7J
(J)
DNA (171-MER)polymer17152800.81Homo sapiens
8K
(K)
Centromere protein Kpolymer26931696.11UniProt (Q9BS16)
Pfam (PF11802)
Homo sapiens (human)CENP-K,Interphase centromere complex protein 37,Protein AF-5alpha,p33
9L
(L)
Centromere protein Lpolymer34439039.61UniProt (Q8N0S6)
Pfam (PF13092)
Homo sapiens (human)CENP-L,Interphase centromere complex protein 33
10M
(M)
Centromere protein Mpolymer18019761.91UniProt (Q9NSP4)
Pfam (PF11111)
Homo sapiens (human)CENP-M,Interphase centromere complex protein 39,Proliferation-associated nuclear element protein 1
11N
(N)
Centromere protein Npolymer33939609.61UniProt (Q96H22)
Pfam (PF05238)
Homo sapiens (human)CENP-N,Interphase centromere complex protein 32
12O
(O)
Centromere protein Opolymer30033830.61UniProt (Q9BU64)
Pfam (PF09496)
Homo sapiens (human)CENP-O,Interphase centromere complex protein 36
13P
(P)
Centromere protein Ppolymer28833210.91UniProt (Q6IPU0)
Pfam (PF13096)
Homo sapiens (human)CENP-P
14Q
(Q)
Centromere protein Qpolymer26830648.41UniProt (Q7L2Z9)
Pfam (PF13094)
Homo sapiens (human)CENP-Q
15R
(R)
Centromere protein Rpolymer17720228.31UniProt (Q13352)
Pfam (PF06729)
Homo sapiens (human)CENP-R,Beta-3-endonexin,Integrin beta-3-binding protein,Nuclear receptor-interacting factor 3
16S
(U)
Centromere protein Upolymer41847609.81UniProt (Q71F23)
Pfam (PF13097)
Homo sapiens (human)CENP-U,Centromere protein of 50 kDa,CENP-50,Interphase centromere complex protein 24,KSHV latent nuclear antigen-interacting protein 1,MLF1-interacting protein,Polo-box-interacting protein 1
17U, V
(k, l)
Centromere protein Cpolymer54461856.02UniProt (Q03188)
Pfam (PF15622)
Pfam (PF15620)
Homo sapiens (human)CENP-C,Centromere autoantigen C,Centromere protein C 1,CENP-C 1,Interphase centromere complex protein 7
18W
(i)
DNA (171-MER)polymer17152747.81Homo sapiens
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains23
Total formula weight751218.6
All*Total formula weight751218.6
*Water molecules are not included.

237423

PDB entries from 2025-06-11

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