7YXO
Crystal structure of WT AncGR2-LBD bound to dexamethasone and SHP coregulator fragment
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E | Ancestral Glucocorticoid Receptor2 | polymer | 248 | 28649.4 | 3 | UniProt (A0A1X8XLE9) Pfam (PF00104) In PDB | unidentified | |
| 2 | B, D, F | SHP NR Box 1 Peptide | polymer | 11 | 1204.4 | 3 | UniProt (Q15466) In PDB | Homo sapiens | Orphan nuclear receptor SHP,Small heterodimer partner,Nuclear receptor subfamily 0 group B member 2 |
| 3 | A, C, E | DEXAMETHASONE | non-polymer | 392.5 | 3 | Chemie (DEX) | |||
| 4 | A, C | 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE | non-polymer | 614.9 | 2 | Chemie (CPS) | |||
| 5 | A, C | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 6 | water | water | 18.0 | 8 | Chemie (HOH) |
Sequence modifications
A, C, E: 530 - 776 (UniProt: A0A1X8XLE9)
| PDB | External Database | Details |
|---|---|---|
| Phe 529 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 89561.4 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 2695.3 | |
| All* | Total formula weight | 92256.7 |
