7YTQ
Human langerin carbohydrate recognition domain in complex with an alpha-mannoside ligand
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | CD207 molecule | polymer | 156 | 17949.0 | 4 | UniProt (G3QPX8) Pfam (PF00059) UniProt (by SIFTS) (Q9UJ71) | Homo sapiens (human) | |
| 2 | E (E) | SER-TRP | polymer | 2 | 291.3 | 1 | unidentified | ||
| 3 | F, I, M, Q (A, B, C, D) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
| 4 | G, J, N, R (A, B, C, D) | ~{N}-[2-[4-[(2~{R},3~{S},4~{S},5~{S},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxyphenyl]ethyl]ethanamide | non-polymer | 341.4 | 4 | Chemie (JMI) | |||
| 5 | H, K, O, S (A, B, C, D) | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
| 6 | L, P (C, D) | TRYPTOPHAN | non-polymer | 204.2 | 2 | Chemie (TRP) | |||
| 7 | T, U, V, W (A, B, C, D) | water | water | 18.0 | 660 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 188 - 328 (UniProt: G3QPX8)
| PDB | External Database | Details |
|---|---|---|
| Ala 173 | - | expression tag |
| Ser 174 | - | expression tag |
| Trp 175 | - | expression tag |
| Ser 176 | - | expression tag |
| His 177 | - | expression tag |
| Pro 178 | - | expression tag |
| Gln 179 | - | expression tag |
| Phe 180 | - | expression tag |
| Glu 181 | - | expression tag |
| Lys 182 | - | expression tag |
| Ile 183 | - | expression tag |
| Glu 184 | - | expression tag |
| Gly 185 | - | expression tag |
| Arg 186 | - | expression tag |
| Met 187 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 72087.4 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 2076.0 | |
| All* | Total formula weight | 74163.4 |
