7YTQ

Human langerin carbohydrate recognition domain in complex with an alpha-mannoside ligand

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	CD207 molecule	polymer	156	17949.0	4	UniProt (G3QPX8) Pfam (PF00059) UniProt (by SIFTS) (Q9UJ71) In PDB	Homo sapiens (human)
2	E	SER-TRP	polymer	2	291.3	1		unidentified
3	A, B, C, D	CALCIUM ION	non-polymer		40.1	4	Chemie (CA)
4	A, B, C, D	~{N}-[2-[4-[(2~{R},3~{S},4~{S},5~{S},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxyphenyl]ethyl]ethanamide	non-polymer		341.4	4	Chemie (JMI)
5	A, B, C, D	CHLORIDE ION	non-polymer		35.5	4	Chemie (CL)
6	C, D	TRYPTOPHAN	non-polymer		204.2	2	Chemie (TRP)
7		water	water		18.0	660	Chemie (HOH)

Sequence modifications

A, B, C, D: 188 - 328 (UniProt: G3QPX8)

PDB	External Database	Details
Ala 173	-	expression tag
Ser 174	-	expression tag
Trp 175	-	expression tag
Ser 176	-	expression tag
His 177	-	expression tag
Pro 178	-	expression tag
Gln 179	-	expression tag
Phe 180	-	expression tag
Glu 181	-	expression tag
Lys 182	-	expression tag
Ile 183	-	expression tag
Glu 184	-	expression tag
Gly 185	-	expression tag
Arg 186	-	expression tag
Met 187	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	72087.4
Non-Polymers*	Number of molecules	14
	Total formula weight	2076.0
All*	Total formula weight	74163.4

*Water molecules are not included.