7YTN

Crystal structure of SARS-CoV-2 Alpha RBD in complex with the D27LEY neutralizing antibody Fab fragment

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	H	Heavy chain of Fab	polymer	239	25335.3	1		Homo sapiens
2	L	Light chain of Fab	polymer	239	26249.2	1		Homo sapiens
3	C	Spike protein S1	polymer	262	29314.2	1	UniProt (P0DTC2) Pfam (PF09408) In PDB	Severe acute respiratory syndrome coronavirus 2

Sequence modifications

C: 319 - 541 (UniProt: P0DTC2)

PDB	External Database	Details
Met 280	-	initiating methionine
Val 281	-	expression tag
Leu 282	-	expression tag
Val 283	-	expression tag
Asn 284	-	expression tag
Gln 285	-	expression tag
Ser 286	-	expression tag
His 287	-	expression tag
Gln 288	-	expression tag
Gly 289	-	expression tag
Phe 290	-	expression tag
Asn 291	-	expression tag
Lys 292	-	expression tag
Glu 293	-	expression tag
His 294	-	expression tag
Thr 295	-	expression tag
Ser 296	-	expression tag
Lys 297	-	expression tag
Met 298	-	expression tag
Val 299	-	expression tag
Ser 300	-	expression tag
Ala 301	-	expression tag
Ile 302	-	expression tag
Val 303	-	expression tag
Leu 304	-	expression tag
Tyr 305	-	expression tag
Val 306	-	expression tag
Leu 307	-	expression tag
Leu 308	-	expression tag
Ala 309	-	expression tag
Ala 310	-	expression tag
Ala 311	-	expression tag
Ala 312	-	expression tag
His 313	-	expression tag
Ser 314	-	expression tag
Ala 315	-	expression tag
Phe 316	-	expression tag
Ala 317	-	expression tag
Ala 318	-	expression tag
Tyr 501	Asn 501	variant

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	80898.7
All*	Total formula weight	80898.7

*Water molecules are not included.