7YSJ

GluK1-1a in nanodisc captured in SYM2081 bound desensitized state

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Glutamate receptor	polymer	1098	124527.1	4	UniProt (A0A0G2K830) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060) UniProt (by SIFTS) (P22756)	Rattus norvegicus (Norway rat)

Sequence modifications

A, B, C, D: 1 - 837 (UniProt: A0A0G2K830)

PDB	External Database	Details
Tyr 552	Cys 586	engineered mutation
Val 557	Cys 591	engineered mutation
Leu 838	-	expression tag
Val 839	-	expression tag
Pro 840	-	expression tag
Arg 841	-	expression tag
Gly 842	-	expression tag
Ser 843	-	expression tag
Ala 844	-	expression tag
Ala 845	-	expression tag
Ala 846	-	expression tag
Ala 847	-	expression tag
Val 848	-	expression tag
Ser 849	-	expression tag
Lys 850	-	expression tag
Gly 851	-	expression tag
Glu 852	-	expression tag
Glu 853	-	expression tag
Leu 854	-	expression tag
Phe 855	-	expression tag
Thr 856	-	expression tag
Gly 857	-	expression tag
Val 858	-	expression tag
Val 859	-	expression tag
Pro 860	-	expression tag
Ile 861	-	expression tag
Leu 862	-	expression tag
Val 863	-	expression tag
Glu 864	-	expression tag
Leu 865	-	expression tag
Asp 866	-	expression tag
Gly 867	-	expression tag
Asp 868	-	expression tag
Val 869	-	expression tag
Asn 870	-	expression tag
Gly 871	-	expression tag
His 872	-	expression tag
Lys 873	-	expression tag
Phe 874	-	expression tag
Ser 875	-	expression tag
Val 876	-	expression tag
Ser 877	-	expression tag
Gly 878	-	expression tag
Glu 879	-	expression tag
Gly 880	-	expression tag
Glu 881	-	expression tag
Gly 882	-	expression tag
Asp 883	-	expression tag
Ala 884	-	expression tag
Thr 885	-	expression tag
Tyr 886	-	expression tag
Gly 887	-	expression tag
Lys 888	-	expression tag
Leu 889	-	expression tag
Thr 890	-	expression tag
Leu 891	-	expression tag
Lys 892	-	expression tag
Phe 893	-	expression tag
Ile 894	-	expression tag
Cys 895	-	expression tag
Thr 896	-	expression tag
Thr 897	-	expression tag
Gly 898	-	expression tag
Lys 899	-	expression tag
Leu 900	-	expression tag
Pro 901	-	expression tag
Val 902	-	expression tag
Pro 903	-	expression tag
Trp 904	-	expression tag
Pro 905	-	expression tag
Thr 906	-	expression tag
Leu 907	-	expression tag
Val 908	-	expression tag
Thr 909	-	expression tag
Thr 910	-	expression tag
Leu 911	-	expression tag
Thr 912	-	expression tag
Tyr 913	-	expression tag
Gly 914	-	expression tag
Val 915	-	expression tag
Gln 916	-	expression tag
Cys 917	-	expression tag
Phe 918	-	expression tag
Ser 919	-	expression tag
Arg 920	-	expression tag
Tyr 921	-	expression tag
Pro 922	-	expression tag
Asp 923	-	expression tag
His 924	-	expression tag
Met 925	-	expression tag
Lys 926	-	expression tag
Gln 927	-	expression tag
His 928	-	expression tag
Asp 929	-	expression tag
Phe 930	-	expression tag
Phe 931	-	expression tag
Lys 932	-	expression tag
Ser 933	-	expression tag
Ala 934	-	expression tag
Met 935	-	expression tag
Pro 936	-	expression tag
Glu 937	-	expression tag
Gly 938	-	expression tag
Tyr 939	-	expression tag
Val 940	-	expression tag
Gln 941	-	expression tag
Glu 942	-	expression tag
Arg 943	-	expression tag
Thr 944	-	expression tag
Ile 945	-	expression tag
Phe 946	-	expression tag
Phe 947	-	expression tag
Lys 948	-	expression tag
Asp 949	-	expression tag
Asp 950	-	expression tag
Gly 951	-	expression tag
Asn 952	-	expression tag
Tyr 953	-	expression tag
Lys 954	-	expression tag
Thr 955	-	expression tag
Arg 956	-	expression tag
Ala 957	-	expression tag
Glu 958	-	expression tag
Val 959	-	expression tag
Lys 960	-	expression tag
Phe 961	-	expression tag
Glu 962	-	expression tag
Gly 963	-	expression tag
Asp 964	-	expression tag
Thr 965	-	expression tag
Leu 966	-	expression tag
Val 967	-	expression tag
Asn 968	-	expression tag
Arg 969	-	expression tag
Ile 970	-	expression tag
Glu 971	-	expression tag
Leu 972	-	expression tag
Lys 973	-	expression tag
Gly 974	-	expression tag
Ile 975	-	expression tag
Asp 976	-	expression tag
Phe 977	-	expression tag
Lys 978	-	expression tag
Glu 979	-	expression tag
Asp 980	-	expression tag
Gly 981	-	expression tag
Asn 982	-	expression tag
Ile 983	-	expression tag
Leu 984	-	expression tag
Gly 985	-	expression tag
His 986	-	expression tag
Lys 987	-	expression tag
Leu 988	-	expression tag
Glu 989	-	expression tag
Tyr 990	-	expression tag
Asn 991	-	expression tag
Tyr 992	-	expression tag
Asn 993	-	expression tag
Ser 994	-	expression tag
His 995	-	expression tag
Asn 996	-	expression tag
Val 997	-	expression tag
Tyr 998	-	expression tag
Ile 999	-	expression tag
Met 1000	-	expression tag
Ala 1001	-	expression tag
Asp 1002	-	expression tag
Lys 1003	-	expression tag
Gln 1004	-	expression tag
Lys 1005	-	expression tag
Asn 1006	-	expression tag
Gly 1007	-	expression tag
Ile 1008	-	expression tag
Lys 1009	-	expression tag
Val 1010	-	expression tag
Asn 1011	-	expression tag
Phe 1012	-	expression tag
Lys 1013	-	expression tag
Ile 1014	-	expression tag
Arg 1015	-	expression tag
His 1016	-	expression tag
Asn 1017	-	expression tag
Ile 1018	-	expression tag
Glu 1019	-	expression tag
Asp 1020	-	expression tag
Gly 1021	-	expression tag
Ser 1022	-	expression tag
Val 1023	-	expression tag
Gln 1024	-	expression tag
Leu 1025	-	expression tag
Ala 1026	-	expression tag
Asp 1027	-	expression tag
His 1028	-	expression tag
Tyr 1029	-	expression tag
Gln 1030	-	expression tag
Gln 1031	-	expression tag
Asn 1032	-	expression tag
Thr 1033	-	expression tag
Pro 1034	-	expression tag
Ile 1035	-	expression tag
Gly 1036	-	expression tag
Asp 1037	-	expression tag
Gly 1038	-	expression tag
Pro 1039	-	expression tag
Val 1040	-	expression tag
Leu 1041	-	expression tag
Leu 1042	-	expression tag
Pro 1043	-	expression tag
Asp 1044	-	expression tag
Asn 1045	-	expression tag
His 1046	-	expression tag
Tyr 1047	-	expression tag
Leu 1048	-	expression tag
Ser 1049	-	expression tag
Thr 1050	-	expression tag
Gln 1051	-	expression tag
Ser 1052	-	expression tag
Lys 1053	-	expression tag
Leu 1054	-	expression tag
Ser 1055	-	expression tag
Lys 1056	-	expression tag
Asp 1057	-	expression tag
Pro 1058	-	expression tag
Asn 1059	-	expression tag
Glu 1060	-	expression tag
Lys 1061	-	expression tag
Arg 1062	-	expression tag
Asp 1063	-	expression tag
His 1064	-	expression tag
Met 1065	-	expression tag
Val 1066	-	expression tag
Leu 1067	-	expression tag
Leu 1068	-	expression tag
Glu 1069	-	expression tag
Phe 1070	-	expression tag
Val 1071	-	expression tag
Thr 1072	-	expression tag
Ala 1073	-	expression tag
Ala 1074	-	expression tag
Gly 1075	-	expression tag
Ile 1076	-	expression tag
Thr 1077	-	expression tag
Leu 1078	-	expression tag
Gly 1079	-	expression tag
Met 1080	-	expression tag
Asp 1081	-	expression tag
Glu 1082	-	expression tag
Leu 1083	-	expression tag
Tyr 1084	-	expression tag
Lys 1085	-	expression tag
Ser 1086	-	expression tag
Gly 1087	-	expression tag
Leu 1088	-	expression tag
Arg 1089	-	expression tag
Ser 1090	-	expression tag
His 1091	-	expression tag
His 1092	-	expression tag
His 1093	-	expression tag
His 1094	-	expression tag
His 1095	-	expression tag
His 1096	-	expression tag
His 1097	-	expression tag
His 1098	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	498108.5
All*	Total formula weight	498108.5

*Water molecules are not included.