7YQY
SARS-CoV-2 BA.2.75 S Trimer in complex with S309 (state2)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Spike glycoprotein | polymer | 1270 | 141125.5 | 3 | UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) | Severe acute respiratory syndrome coronavirus 2 | S glycoprotein,E2,Peplomer protein |
| 2 | D, E, I (F, G, E) | S309 light chain | polymer | 214 | 23204.7 | 3 | Homo sapiens | ||
| 3 | F, G, H (H, I, J) | S309 heavy chain | polymer | 126 | 13918.4 | 3 | Homo sapiens | ||
| 4 | J, K, L, N, O... (D, K, L, N, O...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 9 | In PDB GlyTouCan (G42666HT) | |||
| 5 | M, Q, U (M, Q, U) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 732.7 | 3 | In PDB GlyTouCan (G32152BH) | |||
| 6 | AA, AB, BA, BB, CA... (A, C, B, J) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 45 | Chemie (NAG) |
Sequence modifications
A, B, C: 4 - 1273 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Ile 22 | Thr 19 | variant |
| - | Leu 24 | deletion |
| - | Pro 25 | deletion |
| - | Pro 26 | deletion |
| Ser 27 | Ala 27 | variant |
| Asp 142 | Gly 142 | variant |
| Glu 147 | Lys 147 | variant |
| Arg 152 | Trp 152 | variant |
| Leu 157 | Phe 157 | variant |
| Val 210 | Ile 210 | variant |
| Gly 213 | Val 213 | variant |
| Ser 257 | Gly 257 | variant |
| His 339 | Gly 339 | variant |
| Phe 371 | Ser 371 | variant |
| Pro 373 | Ser 373 | variant |
| Phe 375 | Ser 375 | variant |
| Ala 376 | Thr 376 | variant |
| Asn 405 | Asp 405 | variant |
| Ser 408 | Arg 408 | variant |
| Asn 417 | Lys 417 | variant |
| Lys 440 | Asn 440 | variant |
| Ser 446 | Gly 446 | variant |
| Lys 460 | Asn 460 | variant |
| Asn 477 | Ser 477 | variant |
| Lys 478 | Thr 478 | variant |
| Ala 484 | Glu 484 | variant |
| Arg 498 | Gln 498 | variant |
| Tyr 501 | Asn 501 | variant |
| His 505 | Tyr 505 | variant |
| Gly 614 | Asp 614 | variant |
| Tyr 655 | His 655 | variant |
| Lys 679 | Asn 679 | variant |
| His 681 | Pro 681 | variant |
| Ala 683 | Arg 683 | engineered mutation |
| Ala 685 | Arg 685 | engineered mutation |
| Lys 764 | Asn 764 | variant |
| Tyr 796 | Asp 796 | variant |
| Pro 817 | Phe 817 | engineered mutation |
| Pro 892 | Ala 892 | engineered mutation |
| Pro 899 | Ala 899 | engineered mutation |
| Pro 942 | Ala 942 | engineered mutation |
| His 954 | Gln 954 | variant |
| Lys 969 | Asn 969 | variant |
| Pro 986 | Lys 986 | engineered mutation |
| Pro 987 | Val 987 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 534746.1 | |
| Branched | Number of molecules | 12 |
| Total formula weight | 6017.7 | |
| Non-Polymers* | Number of molecules | 45 |
| Total formula weight | 9954.4 | |
| All* | Total formula weight | 550718.1 |
