7YOJ
Structure of CasPi with guide RNA and target DNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | CasPi | polymer | 867 | 98731.2 | 1 | UniProt (A0A399WQY8) | Armatimonadota bacterium | Reverse transcriptase domain-containing protein |
| 2 | B (C) | DNA (5'-D(P*CP*GP*GP*GP*AP*TP*GP*CP*CP*CP*AP*G)-3') | polymer | 12 | 3688.4 | 1 | Armatimonadetes bacterium | ||
| 3 | C (D) | DNA (30-MER) | polymer | 30 | 9192.9 | 1 | Armatimonadetes bacterium | ||
| 4 | D (B) | RNA (174-MER) | polymer | 174 | 56411.7 | 1 | Armatimonadetes bacterium |
Sequence modifications
A: 1 - 867 (UniProt: A0A399WQY8)
| PDB | External Database | Details |
|---|---|---|
| Ala 537 | Asp 537 | engineered mutation |
| Ala 643 | Glu 643 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 168024.2 | |
| All* | Total formula weight | 168024.2 |
