7YO0
Cryo-EM structure of human Slo1-LRRC26 complex with Symmetry Expansion
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G (A, C, E, G) | Calcium-activated potassium channel subunit alpha-1 | polymer | 1060 | 119458.5 | 4 | UniProt (A0A1W2PRB0) Pfam (PF00520) Pfam (PF07885) Pfam (PF22614) Pfam (PF03493) Pfam (PF21014) UniProt (by SIFTS) (Q12791) | Homo sapiens (human) | Calcium-activated potassium channel,subfamily M subunit alpha-1,K(VCA)alpha,KCa1.1 |
| 2 | B, D, F, H (B, D, F, H) | Leucine-rich repeat-containing protein 26 | polymer | 334 | 34893.6 | 4 | UniProt (Q2I0M4) Pfam (PF13855) | Homo sapiens (human) | BK channel auxiliary gamma subunit LRRC26 |
| 3 | I, M, Q, U (A, C, E, G) | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate | non-polymer | 749.0 | 4 | Chemie (PGW) | |||
| 4 | J, N, R, V (A, C, E, G) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 5 | K, L, O, P, S... (A, C, E, G) | CALCIUM ION | non-polymer | 40.1 | 8 | Chemie (CA) |
Sequence modifications
A, C, E, G: 1 - 1056 (UniProt: A0A1W2PRB0)
| PDB | External Database | Details |
|---|---|---|
| Ser 577 | Lys 646 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 617408.5 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 3413.9 | |
| All* | Total formula weight | 620822.4 |
