7YKJ

Omicron RBDs bound with P3E6 Fab (one up and one down)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (B, C)	Spike glycoprotein	polymer	1205	133912.0	2	UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601)	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)	S glycoprotein,E2,Peplomer protein
2	C (A)	P3E6 heavy chain	polymer	121	13242.7	1		Homo sapiens (human)
3	D (D)	P3E6 light chain	polymer	109	11741.0	1		Homo sapiens (human)

Sequence modifications

B, C: 4 - 1208 (UniProt: P0DTC2)

PDB	External Database	Details
Val 70	Ala 67	variant
-	His 69	deletion
-	Val 70	deletion
Ile 96	Thr 95	variant
Asp 143	Gly 142	variant
-	Val 143	deletion
-	Tyr 144	deletion
-	Tyr 145	deletion
-	Asn 211	deletion
Ile 209	Leu 212	variant
Glu 212	-	insertion
Pro 213	-	insertion
Glu 214	-	insertion
Asp 339	Gly 339	variant
Leu 371	Ser 371	variant
Pro 373	Ser 373	variant
Phe 375	Ser 375	variant
Asn 417	Lys 417	variant
Lys 440	Asn 440	variant
Ser 446	Gly 446	variant
Asn 477	Ser 477	variant
Lys 478	Thr 478	variant
Ala 484	Glu 484	variant
Arg 493	Gln 493	variant
Ser 496	Gly 496	variant
Arg 498	Gln 498	variant
Tyr 501	Asn 501	variant
His 505	Tyr 505	variant
Lys 547	Thr 547	variant
Gly 614	Asp 614	variant
Tyr 655	His 655	variant
Lys 679	Asn 679	variant
His 681	Pro 681	variant
Gly 682	Arg 682	engineered mutation
Ser 683	Arg 683	engineered mutation
Ser 685	Arg 685	engineered mutation
Lys 764	Asn 764	variant
Tyr 796	Asp 796	variant
Lys 856	Asn 856	variant
His 954	Gln 954	variant
Lys 969	Asn 969	variant
Phe 981	Leu 981	variant
Pro 986	Lys 986	engineered mutation
Pro 987	Val 987	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	292807.7
All*	Total formula weight	292807.7

*Water molecules are not included.