7YI5
Cryo-EM structure of Rpd3S complex bound to H3K36me3 nucleosome in loose state
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Transcriptional regulatory protein SIN3 | polymer | 1536 | 175047.3 | 1 | UniProt (P22579) Pfam (PF02671) Pfam (PF08295) Pfam (PF16879) In PDB | Saccharomyces cerevisiae S288C (baker's yeast) | |
| 2 | B | Histone deacetylase RPD3 | polymer | 433 | 48962.0 | 1 | UniProt (P32561) Pfam (PF00850) In PDB | Saccharomyces cerevisiae S288C (baker's yeast) | Transcriptional regulatory protein RPD3 |
| 3 | C, E | Chromatin modification-related protein EAF3 | polymer | 401 | 45266.4 | 2 | UniProt (Q12432) Pfam (PF11717) Pfam (PF22732) Pfam (PF05712) In PDB | Saccharomyces cerevisiae S288C (baker's yeast) | ESA1-associated factor 3 |
| 4 | D, F | Transcriptional regulatory protein RCO1 | polymer | 684 | 78951.3 | 2 | UniProt (Q04779) Pfam (PF00628) In PDB | Saccharomyces cerevisiae S288C (baker's yeast) | |
| 5 | H, L | Histone H4 | polymer | 102 | 11263.2 | 2 | UniProt (P62799) Pfam (PF15511) In PDB | Xenopus laevis (African clawed frog) | |
| 6 | I, M | Histone H2A | polymer | 129 | 13978.2 | 2 | UniProt (Q6AZJ8) Pfam (PF00125) Pfam (PF16211) UniProt (by SIFTS) (P06897) In PDB | Xenopus laevis (African clawed frog) | |
| 7 | J, N | Histone H2B 1.1 | polymer | 122 | 13524.8 | 2 | UniProt (P02281) Pfam (PF00125) In PDB | Xenopus laevis (African clawed frog) | H2B1.1 |
| 8 | O | Wisdom 601 DNA (167-MER) | polymer | 167 | 51308.7 | 1 | synthetic construct | ||
| 9 | P | Wisdom 601 DNA (167-MER) | polymer | 167 | 51798.0 | 1 | synthetic construct | ||
| 10 | G, K | Histone H3 | polymer | 135 | 15346.0 | 2 | UniProt (A0A310TTQ1) Pfam (PF00125) UniProt (by SIFTS) (P84233) In PDB | Xenopus laevis (African clawed frog) | |
| 11 | B, D | ZINC ION | non-polymer | 65.4 | 5 | Chemie (ZN) |
Sequence modifications
J, N: 1 - 122 (UniProt: P02281)
| PDB | External Database | Details |
|---|---|---|
| Thr 29 | Ser 33 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 16 |
| Total formula weight | 683775.8 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 327.0 | |
| All* | Total formula weight | 684102.8 |
