7YI1
Cryo-EM structure of Eaf3 CHD bound to H3K36me3 nucleosome
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (B, F) | Histone H4 | polymer | 102 | 11263.2 | 2 | UniProt (P62799) Pfam (PF15511) | Xenopus laevis (African clawed frog) | |
| 2 | B, E (C, G) | Histone H2A | polymer | 129 | 13978.2 | 2 | UniProt (Q6AZJ8) Pfam (PF00125) Pfam (PF16211) UniProt (by SIFTS) (P06897) | Xenopus laevis (African clawed frog) | |
| 3 | C, F (D, H) | Histone H2B 1.1 | polymer | 122 | 13524.8 | 2 | UniProt (P02281) Pfam (PF00125) | Xenopus laevis (African clawed frog) | H2B1.1 |
| 4 | G (I) | Wisdom 601 DNA (167-MER) | polymer | 167 | 51308.7 | 1 | synthetic construct | ||
| 5 | H (J) | Wisdom 601 DNA (167-MER) | polymer | 167 | 51798.0 | 1 | synthetic construct | ||
| 6 | I, J (K, L) | Chromatin modification-related protein EAF3 | polymer | 401 | 45266.4 | 2 | UniProt (Q12432) Pfam (PF11717) Pfam (PF22732) Pfam (PF05712) | Saccharomyces cerevisiae S288C | ESA1-associated factor 3 |
| 7 | K, L (A, E) | Histone H3 | polymer | 135 | 15346.0 | 2 | UniProt (A0A310TTQ1) Pfam (PF00125) UniProt (by SIFTS) (P84233) | Xenopus laevis (African clawed frog) |
Sequence modifications
D, H: 1 - 122 (UniProt: P02281)
| PDB | External Database | Details |
|---|---|---|
| Thr 29 | Ser 33 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 301864.0 | |
| All* | Total formula weight | 301864.0 |
