7YFR

Structure of GluN1a E698C-GluN2D NMDA receptor in cystines non-crosslinked state.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	Glutamate receptor ionotropic, NMDA 1	polymer	847	95210.1	2	UniProt (Q05586) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060) In PDB	Homo sapiens (human)	GluN1,Glutamate [NMDA] receptor subunit zeta-1,N-methyl-D-aspartate receptor subunit NR1,NMD-R1
2	B, D	Glutamate receptor ionotropic, NMDA 2D	polymer	891	97187.4	2	UniProt (O15399) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060) In PDB	Homo sapiens (human)	GluN2D,EB11,Glutamate [NMDA] receptor subunit epsilon-4,N-methyl D-aspartate receptor subtype 2D,NMDAR2D,NR2D
3	E, F, G, H, I...	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	7	In PDB GlyTouCan (G42666HT)
4	A, C	GLYCINE	non-polymer		75.1	2	Chemie (GLY)
5	A, C	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	5	Chemie (NAG)
6	B, D	GLUTAMIC ACID	non-polymer		147.1	2	Chemie (GLU)

Sequence modifications

A, C: 1 - 847 (UniProt: Q05586)

PDB	External Database	Details
Cys 698	Glu 698	engineered mutation

B, D: 1 - 879 (UniProt: O15399)

PDB	External Database	Details
Phe 662	Trp 662	conflict
Ala 880	-	expression tag
Ala 881	-	expression tag
Ser 882	-	expression tag
Ala 883	-	expression tag
Trp 884	-	expression tag
Ser 885	-	expression tag
His 886	-	expression tag
Pro 887	-	expression tag
Gln 888	-	expression tag
Phe 889	-	expression tag
Glu 890	-	expression tag
Lys 891	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	384795.0
Branched	Number of molecules	7
	Total formula weight	2970.8
Non-Polymers*	Number of molecules	9
	Total formula weight	1550.4
All*	Total formula weight	389316.2

*Water molecules are not included.