7YFL

Structure of GluN1a-GluN2D NMDA receptor in complex with agonists glycine and glutamate.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	Glutamate receptor ionotropic, NMDA 1	polymer	847	95236.1	2	UniProt (Q05586) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060)	Homo sapiens (human)	GluN1,Glutamate [NMDA] receptor subunit zeta-1,N-methyl-D-aspartate receptor subunit NR1,NMD-R1
2	B, D (B, D)	Glutamate receptor ionotropic, NMDA 2D	polymer	891	97226.4	2	UniProt (O15399) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060)	Homo sapiens (human)	GluN2D,EB11,Glutamate [NMDA] receptor subunit epsilon-4,N-methyl D-aspartate receptor subtype 2D,NMDAR2D,NR2D
3	E, F, G, H (E, F, G, H)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	4	In PDB GlyTouCan (G42666HT)
4	I, P (A, C)	GLYCINE	non-polymer		75.1	2	Chemie (GLY)
5	J, K, L, M, N... (A, C)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	10	Chemie (NAG)
6	O, V (B, D)	GLUTAMIC ACID	non-polymer		147.1	2	Chemie (GLU)

Sequence modifications

B, D: 1 - 879 (UniProt: O15399)

PDB	External Database	Details
Ala 880	-	expression tag
Ala 881	-	expression tag
Ser 882	-	expression tag
Ala 883	-	expression tag
Trp 884	-	expression tag
Ser 885	-	expression tag
His 886	-	expression tag
Pro 887	-	expression tag
Gln 888	-	expression tag
Phe 889	-	expression tag
Glu 890	-	expression tag
Lys 891	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	384925.0
Branched	Number of molecules	4
	Total formula weight	1697.6
Non-Polymers*	Number of molecules	14
	Total formula weight	2656.5
All*	Total formula weight	389279.1

*Water molecules are not included.