7YCK

Crystal structure of SARS-CoV-2 Spike RBD in complex with FP-12A Fab

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (A, B)	Spike protein S1	polymer	204	23047.8	2	UniProt (P0DTC2) Pfam (PF09408)	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2)
2	B, E (C, E)	FP-12A Fab heavy chain	polymer	224	23925.7	2		Homo sapiens
3	C, F (D, F)	FP-12A Fab light chain	polymer	216	23124.3	2		Homo sapiens
4	G (G)	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		732.7	1	In PDB GlyTouCan (G32152BH)
5	H (H)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		570.5	1	In PDB GlyTouCan (G21290RB)
6	I, J, K, L, M... (A, C, D, B, E...)	water	water		18.0	127	Chemie (HOH)

Sequence modifications

A, B: 333 - 530 (UniProt: P0DTC2)

PDB	External Database	Details
His 531	-	expression tag
His 532	-	expression tag
His 533	-	expression tag
His 534	-	expression tag
His 535	-	expression tag
His 536	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	140195.7
Branched	Number of molecules	2
	Total formula weight	1303.2
All*	Total formula weight	141499.0

*Water molecules are not included.