7YC3
Crystal structure of FGFR4 kinase domain with 10t
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Fibroblast growth factor receptor 4 | polymer | 311 | 34695.1 | 1 | UniProt (P22455) Pfam (PF07714) In PDB | Homo sapiens (human) | FGFR-4 |
2 | A | 6-bromanyl-~{N}-[5-cyano-4-(2-methoxyethylamino)pyridin-2-yl]-5-methanoyl-1-(2-morpholin-4-ylethyl)pyrrolo[3,2-b]pyridine-3-carboxamide | non-polymer | 556.4 | 1 | Chemie (IIW) | |||
3 | A | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
4 | A | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
5 | water | water | 18.0 | 234 | Chemie (HOH) |
Sequence modifications
A: 445 - 753 (UniProt: P22455)
PDB | External Database | Details |
---|---|---|
Gly 443 | - | expression tag |
Pro 444 | - | expression tag |
Glu 664 | Arg 664 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 34695.1 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 1120.9 | |
All* | Total formula weight | 35815.9 |