7YAW
Crystal structure of ZAK in complex with compound YH-180
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (D, A, B, C) | Mitogen-activated protein kinase kinase kinase MLT | polymer | 310 | 35337.5 | 4 | UniProt (Q9NYL2) Pfam (PF07714) | Homo sapiens (human) | ZAK |
| 2 | E, F, G, H (D, A, B, C) | ~{N}-[3-[[5-[1-[2,6-bis(fluoranyl)-3-[(3-phenylphenyl)sulfonylamino]phenyl]-1,2,3-triazol-4-yl]-1~{H}-pyrazolo[3,4-b]pyridin-3-yl]oxy]propyl]propanamide | non-polymer | 658.7 | 4 | Chemie (IGS) | |||
| 3 | I, J, K, L (D, A, B, C) | water | water | 18.0 | 404 | Chemie (HOH) |
Sequence modifications
D, A, B, C: 5 - 309 (UniProt: Q9NYL2)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
| Ala 1 | - | expression tag |
| Met 2 | - | expression tag |
| Gly 3 | - | expression tag |
| Ser 4 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 141350.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 2634.7 | |
| All* | Total formula weight | 143984.7 |
