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7Y4T

Crystal structure of cMET kinase domain bound by compound 9I

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Hepatocyte growth factor receptorpolymer30934842.31UniProt (P08581)
Pfam (PF07714)
Homo sapiens (human)HGF receptor,HGF/SF receptor,Proto-oncogene c-Met,Scatter factor receptor,SF receptor,Tyrosine-protein kinase Met
2B
(A)
2-[2-[3-(1-methylpyrazol-4-yl)quinolin-6-yl]ethyl]-6-(3-nitrophenyl)pyridazin-3-onenon-polymer452.51Chemie (I90)
3C
(A)
waterwater18.097Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight34842.3
Non-Polymers*Number of molecules1
Total formula weight452.5
All*Total formula weight35294.8
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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